Whole-proteome prediction of protein function via graph-theoretic analysis of interaction maps

Motivation: Determining protein function is one of the most important problems in the post-genomic era. For the typical proteome, there are no functional annotations for one-third or more of its proteins. Recent high-throughput experiments have determined proteome-scale protein physical interaction...

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Veröffentlicht in:	Bioinformatics 2005-06, Vol.21 (suppl-1), p.i302-i310
Hauptverfasser:	Nabieva, Elena, Jim, Kam, Agarwal, Amit, Chazelle, Bernard, Singh, Mona
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Computational Biology - methods Evolution, Molecular Fungal Proteins - chemistry Genomics Models, Statistical Models, Theoretical Protein Interaction Mapping - methods Proteins - chemistry Proteomics - methods
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