Randomized Placebo-Controlled Study of Low-Dose Warfarin for the Prevention of Central Venous Catheter–Associated Thrombosis in Patients With Cancer

In this multicenter, randomized, placebo-controlled clinical trial, we studied whether warfarin 1 mg daily reduces the incidence of symptomatic central venous catheter (CVC) -associated thrombosis in patients with cancer. Two hundred fifty-five patients with cancer who required a CVC for at least 7...

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Veröffentlicht in:	Journal of clinical oncology 2005-06, Vol.23 (18), p.4063-4069
Hauptverfasser:	COUBAN, Stephen, GOODYEAR, Michael, BURNELL, Margot, DOLAN, Sean, WASI, Parveen, BARNES, David, MACLEOD, Darlene, BURTON, Erica, ANDREOU, Pantelis, ANDERSON, David R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anticoagulants - administration & dosage Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Catheterization, Central Venous - adverse effects Catheters, Indwelling - adverse effects Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Double-Blind Method Female Humans Male Medical sciences Middle Aged Neoplasms - drug therapy Placebos Radiography Treatment Outcome Tumors Venous Thrombosis - diagnostic imaging Venous Thrombosis - etiology Venous Thrombosis - prevention & control Warfarin - administration & dosage
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