Proteomic Analysis of Isolated Chlamydomonas Centrioles Reveals Orthologs of Ciliary-Disease Genes

Background: The centriole is one of the most enigmatic organelles in the cell. Centrioles are cylindrical, microtubule-based barrels found in the core of the centrosome. Centrioles also act as basal bodies during interphase to nucleate the assembly of cilia and flagella. There are currently only a h...

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Veröffentlicht in:	Current biology 2005-06, Vol.15 (12), p.1090-1098
Hauptverfasser:	Keller, Lani C., Romijn, Edwin P., Zamora, Ivan, Yates, John R., Marshall, Wallace F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Centrioles - genetics Chlamydomonas - genetics Cilia - genetics Cilia - pathology Conserved Sequence Humans Kidney Diseases - genetics Molecular Chaperones Nuclear Proteins - genetics Orofaciodigital Syndromes - genetics Proteins - genetics Proteomics - methods Protozoan Proteins - analysis Protozoan Proteins - genetics Reproducibility of Results
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