Adiponectin activates c-Jun NH2-terminal kinase and inhibits signal transducer and activator of transcription 3

Adiponectin, a major adipose cytokine, plays a crucial role in the inhibition of metabolic syndrome by acting on such cell types as muscle cells and hepatocytes. Furthermore, evidence suggests that adiponectin may influence cancer pathogenesis. Adiponectin occurs in non-proteolytic (full-length adip...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-07, Vol.333 (1), p.79-87
Hauptverfasser:	Miyazaki, Toshiaki, Bub, Jeffrey D, Uzuki, Miwa, Iwamoto, Yoshiki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Animals Cells, Cultured DNA-Binding Proteins - metabolism Enzyme Activation Gene Expression Regulation, Neoplastic Humans Intercellular Signaling Peptides and Proteins - metabolism JNK Mitogen-Activated Protein Kinases - metabolism Myoblasts - metabolism Neoplasms - metabolism Signal Transduction STAT3 Transcription Factor Trans-Activators - metabolism
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