Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the fischer 344 rat

To examine the oxygen-dependence of glucose consumption in solid tumors, we monitored gradients of glucose, lactate, and hypoxia in R3230Ac and FSA tumors growing in Fischer 344 rats. Bioluminescence imaging, detection of Hoechst 33342, and immunostaining of the hypoxia marker EF5 [2-8-N-(2,2,3,3,3-...

Ausführliche Beschreibung