Tissue-dependent alterations in lipid mass in mice lacking glycerol kinase

Glycerol kinase (ATP:glycerol-3-phosphotransferase, EC 2.7.1.30, glycerokinase) (Gyk) has a central role in plasma glycerol extraction and utilization by tissues for lipid biosynthesis. Gyk deficiency causes various phenotypic changes ranging from asymptomatic hyperglycerolemia to a severe metabolic...

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Veröffentlicht in:	Lipids 2005-03, Vol.40 (3), p.287-293
Hauptverfasser:	Golovko, M.Y, Hovda, J.T, Cai, Z.J, Craigen, W.J, Murphy, E.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - anatomy & histology Animal tissues Animals Biosynthesis Brain Chemistry Cholesterol - analysis Gene Targeting glycerol kinase Glycerol Kinase - deficiency Glycerol Kinase - genetics Glycerol Kinase - metabolism Kidney - chemistry Kidneys Liver - chemistry Metabolic disorders Mice Mice, Knockout Muscle, Skeletal - chemistry Myocardium - chemistry Organ Size Organ Specificity phospholipids Phospholipids - analysis Reference Values tissue distribution
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