Systematic immunohistochemical profiling of 378 brain tumors with 37 antibodies using tissue microarray technology

We performed a systematic immunohistochemical study on 378 brain tumors using 37 antibodies and tissue microarray (TMA) technology. The aim of this study was to find new diagnostic biomarkers using antibodies established in our laboratory. Our TMA consisted of a grid of 1.5-mm cores that were extrac...

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Veröffentlicht in:	Acta neuropathologica 2006-05, Vol.111 (5), p.475-482
Hauptverfasser:	Ikota, Hayato, Kinjo, Sawako, Yokoo, Hideaki, Nakazato, Yoichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies - immunology Antigens Aquaporin 4 - immunology Aquaporin 4 - metabolism Astrocytoma - diagnosis Astrocytoma - immunology Astrocytoma - metabolism Basic Helix-Loop-Helix Transcription Factors - immunology Basic Helix-Loop-Helix Transcription Factors - metabolism Biomarkers Biomarkers, Tumor - immunology Biomarkers, Tumor - metabolism Brain cancer Brain Neoplasms - diagnosis Brain Neoplasms - immunology Brain Neoplasms - metabolism Brain research Cluster Analysis Diagnosis, Differential Glial Fibrillary Acidic Protein - immunology Glial Fibrillary Acidic Protein - metabolism Humans Immunohistochemistry - methods Intermediate Filament Proteins - immunology Intermediate Filament Proteins - metabolism Mucin-1 - immunology Mucin-1 - metabolism Nerve Tissue Proteins - immunology Nerve Tissue Proteins - metabolism Nestin Oligodendrocyte Transcription Factor 2 Oligodendroglioma - diagnosis Oligodendroglioma - immunology Oligodendroglioma - metabolism Pathology Prognosis Protein Array Analysis - methods Proteins Tumors Vimentin - immunology Vimentin - metabolism
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