Pyrimidine and Purine Biosynthesis and Degradation in Plants

Nucleotide metabolism operates in all living organisms, embodies an evolutionarily ancient and indispensable complex of metabolic pathways and is of utmost importance for plant metabolism and development. In plants, nucleotides can be synthesized de novo from 5-phosphoribosyl-1-pyrophosphate and sim...

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Veröffentlicht in:Annual review of plant biology 2006-01, Vol.57 (1), p.805-836
Hauptverfasser: Zrenner, R, Stitt, M, Sonnewald, U, Boldt, R
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container_title Annual review of plant biology
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creator Zrenner, R
Stitt, M
Sonnewald, U
Boldt, R
description Nucleotide metabolism operates in all living organisms, embodies an evolutionarily ancient and indispensable complex of metabolic pathways and is of utmost importance for plant metabolism and development. In plants, nucleotides can be synthesized de novo from 5-phosphoribosyl-1-pyrophosphate and simple molecules (e.g., CO(2), amino acids, and tetrahydrofolate), or be derived from preformed nucleosides and nucleobases via salvage reactions. Nucleotides are degraded to simple metabolites, and this process permits the recycling of phosphate, nitrogen, and carbon into central metabolic pools. Despite extensive biochemical knowledge about purine and pyrimidine metabolism, comprehensive studies of the regulation of this metabolism in plants are only starting to emerge. Here we review progress in molecular aspects and recent studies on the regulation and manipulation of nucleotide metabolism in plants.
doi_str_mv 10.1146/annurev.arplant.57.032905.105421
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source Annual Reviews Complete A-Z List; MEDLINE
subjects Amino acids
Biosynthesis
Carbon dioxide
Flowers & plants
Hydrolysis
literature reviews
Metabolism
Metabolites
Molecular biology
nucleosides
Photosynthesis
Plant metabolism
plant physiology
Plants - metabolism
purines
Purines - biosynthesis
Purines - metabolism
pyrimidines
Pyrimidines - biosynthesis
Pyrimidines - metabolism
title Pyrimidine and Purine Biosynthesis and Degradation in Plants
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