Prolonged Indomethacin Exposure Is Associated With Decreased White Matter Injury Detected With Magnetic Resonance Imaging in Premature Newborns at 24 to 28 Weeks' Gestation at Birth

Newborns delivered before 28 weeks' gestation commonly have white matter lesions on MRI that are associated with adverse neurodevelopmental outcomes. Our objective was to determine the risk factors for MRI-detectable white matter injury in infants delivered before 28 weeks' gestation who w...

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Veröffentlicht in:	Pediatrics (Evanston) 2006-05, Vol.117 (5), p.1626-1631
Hauptverfasser:	Miller, Steven P, Mayer, Eleanor E, Clyman, Ronald I, Glidden, David V, Hamrick, Shannon E.G, Barkovich, A. James
Format:	Artikel
Sprache:	eng
Schlagworte:	Babies Biological and medical sciences Brain - drug effects Brain - pathology Brain damage Brain Damage, Chronic - diagnosis Brain Damage, Chronic - prevention & control Care and treatment Cyclooxygenase Inhibitors - administration & dosage Degeneration Ductus Arteriosus, Patent - prevention & control General aspects Gestational Age Health aspects Humans Indomethacin - administration & dosage Infant, Newborn Infant, Premature Infant, Premature, Diseases - diagnosis Infant, Premature, Diseases - prevention & control Infants (Premature) Magnetic Resonance Imaging Medical sciences Nervous system Neurodegenerative diseases Neurology NMR Nuclear magnetic resonance Pediatrics Premature birth Premature infants Risk factors Vascular diseases and vascular malformations of the nervous system
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