Lipopolysaccharide-mediated protection against Klebsiella pneumoniae-induced lobar pneumonia: intranasal vs. intramuscular route of immunization

Immunoprotective potential of delivered lipopolysaccharide (LPS) preparation from Klebsiella pneumoniae was determined in a murine model of lobar pneumonia. Protection was assessed with three doses of LPS (25, 50 and 100 microg; without any adjuvant) administered intranasally or intramuscularly. Aft...

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Veröffentlicht in:	Folia microbiologica 2005, Vol.50 (1), p.83-86
Hauptverfasser:	Yadav, V, Sharma, S, Harjai, K, Mohan, H, Chhibber, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Animals Colony Count, Microbial Disease Models, Animal Immunization India Injections, Intramuscular Klebsiella Infections - microbiology Klebsiella Infections - prevention & control Klebsiella pneumoniae Klebsiella pneumoniae - growth & development Klebsiella pneumoniae - immunology Lipopolysaccharides - administration & dosage Lipopolysaccharides - immunology Lipopolysaccharides - isolation & purification Lung - microbiology Lung - pathology Mice Mice, Inbred BALB C Pneumonia, Bacterial - microbiology Pneumonia, Bacterial - prevention & control
Online-Zugang:	Volltext
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