Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation
Summary Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ tr...
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Veröffentlicht in: | Transplant international 2005-07, Vol.18 (7), p.828-834 |
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creator | Ridgway, Dan M White, Steven A Kimber, Rachel M Nicholson, Michael L |
description | Summary
Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ transplantation. This questionnaire based study examines current patterns of donor pancreas procurement and use. Reasons for non procurement are studied together with the attitudes of transplant professionals to pancreas allocation. The minority of potentially useful pancreata are currently made available to either whole pancreas or islet transplant programs. Whilst professionals appreciate the role of each modality, there is a need to define criteria for pancreas allocation to avoid under use of donor organs. |
doi_str_mv | 10.1111/j.1432-2277.2005.00144.x |
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Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ transplantation. This questionnaire based study examines current patterns of donor pancreas procurement and use. Reasons for non procurement are studied together with the attitudes of transplant professionals to pancreas allocation. The minority of potentially useful pancreata are currently made available to either whole pancreas or islet transplant programs. Whilst professionals appreciate the role of each modality, there is a need to define criteria for pancreas allocation to avoid under use of donor organs.</description><identifier>ISSN: 0934-0874</identifier><identifier>EISSN: 1432-2277</identifier><identifier>DOI: 10.1111/j.1432-2277.2005.00144.x</identifier><identifier>PMID: 15948863</identifier><language>eng</language><publisher>Oxford, UK: Munksgaard International Publishers</publisher><subject>Adolescent ; Adult ; Aged ; Attitude of Health Personnel ; Biological and medical sciences ; Child ; Child, Preschool ; General aspects ; Health Care Rationing - methods ; Humans ; Infant ; Infant, Newborn ; Informed Consent ; islet transplantation ; Islets of Langerhans Transplantation ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; organ donation ; pancreas transplantation ; Pancreas Transplantation - statistics & numerical data ; Pharmacology. Drug treatments ; Surveys and Questionnaires ; Time Factors ; Tissue and Organ Harvesting - methods ; Tissue and Organ Procurement - methods ; Tissue Donors ; United Kingdom</subject><ispartof>Transplant international, 2005-07, Vol.18 (7), p.828-834</ispartof><rights>2006 INIST-CNRS</rights><rights>Copyright Blackwell Publishing Ltd. Jul 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4234-7b8cdd62dccda1a37a7f77c69430aa7ce87e926d55f1fe703c967770d36788963</citedby><cites>FETCH-LOGICAL-c4234-7b8cdd62dccda1a37a7f77c69430aa7ce87e926d55f1fe703c967770d36788963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1432-2277.2005.00144.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1432-2277.2005.00144.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17350879$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15948863$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ridgway, Dan M</creatorcontrib><creatorcontrib>White, Steven A</creatorcontrib><creatorcontrib>Kimber, Rachel M</creatorcontrib><creatorcontrib>Nicholson, Michael L</creatorcontrib><title>Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation</title><title>Transplant international</title><addtitle>Transpl Int</addtitle><description>Summary
Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ transplantation. This questionnaire based study examines current patterns of donor pancreas procurement and use. Reasons for non procurement are studied together with the attitudes of transplant professionals to pancreas allocation. The minority of potentially useful pancreata are currently made available to either whole pancreas or islet transplant programs. Whilst professionals appreciate the role of each modality, there is a need to define criteria for pancreas allocation to avoid under use of donor organs.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Attitude of Health Personnel</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>General aspects</subject><subject>Health Care Rationing - methods</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Informed Consent</subject><subject>islet transplantation</subject><subject>Islets of Langerhans Transplantation</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>organ donation</subject><subject>pancreas transplantation</subject><subject>Pancreas Transplantation - statistics & numerical data</subject><subject>Pharmacology. Drug treatments</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><subject>Tissue and Organ Harvesting - methods</subject><subject>Tissue and Organ Procurement - methods</subject><subject>Tissue Donors</subject><subject>United Kingdom</subject><issn>0934-0874</issn><issn>1432-2277</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkVtrVDEUhYModmz9CxIEfZvTXE5u4osMXkoLQmmfQ5oLZsicHJMcbP-9mc5g0SfzsgP7W5vFWgBAjAbc3_l2wCMla0KEGAhCbEAIj-Nw_wys_iyegxVSdFwjKcYT8KrWLUKISIZeghPM1CglpyvQNkspfmpwLsa2aH2FOUCXp1zgbCZbvKnQpJStaTFPME6w_fDw9vIDDEtbiodxN6d42FYY_pJNDsaafIOtmKnOyUztkTsDL4JJ1b8-zlNw--Xzzebb-ur714vNp6u1HUl3Lu6kdY4TZ60z2FBhRBDCcjVSZIywXgqvCHeMBRy8QNQqLoRAjnIhpeL0FLw_3J1L_rn42vQuVutTN-LzUjUXijCGWQff_gNu81Km7k0TrDhhlJIOyQNkS661-KDnEnemPGiM9L4WvdX79PU-fb2vRT_Wou-79M3x_nK38-5JeOyhA--OgKnWpNDzsrE-cYKy3qPq3McD9ysm__DfBvTN9UX_0N_1uqlR</recordid><startdate>200507</startdate><enddate>200507</enddate><creator>Ridgway, Dan M</creator><creator>White, Steven A</creator><creator>Kimber, Rachel M</creator><creator>Nicholson, Michael L</creator><general>Munksgaard International Publishers</general><general>Blackwell Publishing</general><general>Blackwell Publishing Ltd</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200507</creationdate><title>Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation</title><author>Ridgway, Dan M ; White, Steven A ; Kimber, Rachel M ; Nicholson, Michael L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4234-7b8cdd62dccda1a37a7f77c69430aa7ce87e926d55f1fe703c967770d36788963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Attitude of Health Personnel</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>General aspects</topic><topic>Health Care Rationing - methods</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Informed Consent</topic><topic>islet transplantation</topic><topic>Islets of Langerhans Transplantation</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>organ donation</topic><topic>pancreas transplantation</topic><topic>Pancreas Transplantation - statistics & numerical data</topic><topic>Pharmacology. Drug treatments</topic><topic>Surveys and Questionnaires</topic><topic>Time Factors</topic><topic>Tissue and Organ Harvesting - methods</topic><topic>Tissue and Organ Procurement - methods</topic><topic>Tissue Donors</topic><topic>United Kingdom</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ridgway, Dan M</creatorcontrib><creatorcontrib>White, Steven A</creatorcontrib><creatorcontrib>Kimber, Rachel M</creatorcontrib><creatorcontrib>Nicholson, Michael L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Transplant international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ridgway, Dan M</au><au>White, Steven A</au><au>Kimber, Rachel M</au><au>Nicholson, Michael L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation</atitle><jtitle>Transplant international</jtitle><addtitle>Transpl Int</addtitle><date>2005-07</date><risdate>2005</risdate><volume>18</volume><issue>7</issue><spage>828</spage><epage>834</epage><pages>828-834</pages><issn>0934-0874</issn><eissn>1432-2277</eissn><abstract>Summary
Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ transplantation. This questionnaire based study examines current patterns of donor pancreas procurement and use. Reasons for non procurement are studied together with the attitudes of transplant professionals to pancreas allocation. The minority of potentially useful pancreata are currently made available to either whole pancreas or islet transplant programs. Whilst professionals appreciate the role of each modality, there is a need to define criteria for pancreas allocation to avoid under use of donor organs.</abstract><cop>Oxford, UK</cop><pub>Munksgaard International Publishers</pub><pmid>15948863</pmid><doi>10.1111/j.1432-2277.2005.00144.x</doi><tpages>7</tpages></addata></record> |
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subjects | Adolescent Adult Aged Attitude of Health Personnel Biological and medical sciences Child Child, Preschool General aspects Health Care Rationing - methods Humans Infant Infant, Newborn Informed Consent islet transplantation Islets of Langerhans Transplantation Medical sciences Middle Aged Nephrology. Urinary tract diseases organ donation pancreas transplantation Pancreas Transplantation - statistics & numerical data Pharmacology. Drug treatments Surveys and Questionnaires Time Factors Tissue and Organ Harvesting - methods Tissue and Organ Procurement - methods Tissue Donors United Kingdom |
title | Current practices of donor pancreas allocation in the UK: future implications for pancreas and islet transplantation |
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