Use of microsatellite markers to detect quantitative trait loci in yorkshire pigs
To identify genetic markers associated with economic traits in pigs, 157 microsatellite markers were examined in Yorkshire pigs. Thirty eight female Yorkshire pigs were initially examined and six of them were selected as progenitors; half were more than 1.5 standard deviations (SD) above the mean fo...
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| Veröffentlicht in: | Journal of Reproduction and Development 2006, Vol.52(2), pp.229-237 |
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| creator | Kim, C.W.(Jinju National Univ. (Korea R.)) Hong, Y.H Yun, S.I Lee, S.R Kim, Y.H Kim, M.S Chung, K.H Jung, W.Y Kwon, E.J Hwang, S.S Park, D.H Cho, K. K Lee, J.G Kim, B.W Kim, J.W Kang, Y.S Yeo, J.S Chang, K.T |
| description | To identify genetic markers associated with economic traits in pigs, 157 microsatellite markers were examined in Yorkshire pigs. Thirty eight female Yorkshire pigs were initially examined and six of them were selected as progenitors; half were more than 1.5 standard deviations (SD) above the mean for average daily gain (ADG) and backfat thickness (BFT), and the remaining half were more than 1.5 SD below the mean. These pigs were then mated to male Duroc pigs, and 200 F2 pig offspring were examined for the association of specific alleles with ADG and BFT. To confirm the specific markers identified in the initial analysis, associations of significant markers with economic traits were further examined in 228 additional performance-tested purebred pigs. Twenty-five microsatellite markers were significantly associated with either ADG or BFT, and among these, 17 were associated with both traits. The markers with the highest association to ADG were also associated with BFT. Our study reveals that specific markers could be used to predict economic significance, and confirms several quantitative trait loci (QTL) identified in previous studies. However, further analysis with more closely-spaced microsatellite markers is required to refine predictive values for economic traits and positions of QTL that are reliable for actual phenotypic prediction. |
| doi_str_mv | 10.1262/jrd.17046 |
| format | Article |
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(Korea R.)) ; Hong, Y.H ; Yun, S.I ; Lee, S.R ; Kim, Y.H ; Kim, M.S ; Chung, K.H ; Jung, W.Y ; Kwon, E.J ; Hwang, S.S ; Park, D.H ; Cho, K. K ; Lee, J.G ; Kim, B.W ; Kim, J.W ; Kang, Y.S ; Yeo, J.S ; Chang, K.T</creator><creatorcontrib>Kim, C.W.(Jinju National Univ. (Korea R.)) ; Hong, Y.H ; Yun, S.I ; Lee, S.R ; Kim, Y.H ; Kim, M.S ; Chung, K.H ; Jung, W.Y ; Kwon, E.J ; Hwang, S.S ; Park, D.H ; Cho, K. K ; Lee, J.G ; Kim, B.W ; Kim, J.W ; Kang, Y.S ; Yeo, J.S ; Chang, K.T</creatorcontrib><description>To identify genetic markers associated with economic traits in pigs, 157 microsatellite markers were examined in Yorkshire pigs. Thirty eight female Yorkshire pigs were initially examined and six of them were selected as progenitors; half were more than 1.5 standard deviations (SD) above the mean for average daily gain (ADG) and backfat thickness (BFT), and the remaining half were more than 1.5 SD below the mean. These pigs were then mated to male Duroc pigs, and 200 F2 pig offspring were examined for the association of specific alleles with ADG and BFT. To confirm the specific markers identified in the initial analysis, associations of significant markers with economic traits were further examined in 228 additional performance-tested purebred pigs. Twenty-five microsatellite markers were significantly associated with either ADG or BFT, and among these, 17 were associated with both traits. The markers with the highest association to ADG were also associated with BFT. Our study reveals that specific markers could be used to predict economic significance, and confirms several quantitative trait loci (QTL) identified in previous studies. However, further analysis with more closely-spaced microsatellite markers is required to refine predictive values for economic traits and positions of QTL that are reliable for actual phenotypic prediction.</description><identifier>ISSN: 0916-8818</identifier><identifier>EISSN: 1348-4400</identifier><identifier>DOI: 10.1262/jrd.17046</identifier><identifier>PMID: 16415521</identifier><language>eng</language><publisher>Japan: THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</publisher><subject>ADG ; Alleles ; Animals ; BACKFAT ; BFT ; CARTE GENETIQUE ; CERDO ; Crosses, Genetic ; Economic trait ; Female ; FORECASTING ; GAIN DE POIDS ; GANANCIA DE PESO ; GENE LOCATION ; GENETIC MAPS ; Genetic Markers ; GENETIC PARAMETERS ; Genetic Techniques ; Genome ; Genotype ; LARD DORSAL ; LOCALISATION DE GENE ; LOCALIZACION DE GENES ; Male ; MAPAS GENETICOS ; Microsatellite marker ; Microsatellite Repeats ; Models, Genetic ; Models, Statistical ; PARAMETRE GENETIQUE ; PARAMETROS GENETICOS ; Phenotype ; Polymerase Chain Reaction ; PORCIN ; QTL ; Quantitative Trait Loci ; SWINE ; TECHNIQUE DE PREVISION ; TECNICAS DE PREDICCION ; TOCINO DORSAL ; WEIGHT GAIN</subject><ispartof>Journal of Reproduction and Development, 2006, Vol.52(2), pp.229-237</ispartof><rights>2006 Society for Reproduction and Development</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-d541b1b55e2db589b373f1b9138e385a5eecfdb43da9ec5cca3be05afb8fb1e23</citedby><cites>FETCH-LOGICAL-c599t-d541b1b55e2db589b373f1b9138e385a5eecfdb43da9ec5cca3be05afb8fb1e23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,1883,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16415521$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, C.W.(Jinju National Univ. (Korea R.))</creatorcontrib><creatorcontrib>Hong, Y.H</creatorcontrib><creatorcontrib>Yun, S.I</creatorcontrib><creatorcontrib>Lee, S.R</creatorcontrib><creatorcontrib>Kim, Y.H</creatorcontrib><creatorcontrib>Kim, M.S</creatorcontrib><creatorcontrib>Chung, K.H</creatorcontrib><creatorcontrib>Jung, W.Y</creatorcontrib><creatorcontrib>Kwon, E.J</creatorcontrib><creatorcontrib>Hwang, S.S</creatorcontrib><creatorcontrib>Park, D.H</creatorcontrib><creatorcontrib>Cho, K. K</creatorcontrib><creatorcontrib>Lee, J.G</creatorcontrib><creatorcontrib>Kim, B.W</creatorcontrib><creatorcontrib>Kim, J.W</creatorcontrib><creatorcontrib>Kang, Y.S</creatorcontrib><creatorcontrib>Yeo, J.S</creatorcontrib><creatorcontrib>Chang, K.T</creatorcontrib><title>Use of microsatellite markers to detect quantitative trait loci in yorkshire pigs</title><title>Journal of Reproduction and Development</title><addtitle>J. Reprod. Dev.</addtitle><description>To identify genetic markers associated with economic traits in pigs, 157 microsatellite markers were examined in Yorkshire pigs. Thirty eight female Yorkshire pigs were initially examined and six of them were selected as progenitors; half were more than 1.5 standard deviations (SD) above the mean for average daily gain (ADG) and backfat thickness (BFT), and the remaining half were more than 1.5 SD below the mean. These pigs were then mated to male Duroc pigs, and 200 F2 pig offspring were examined for the association of specific alleles with ADG and BFT. To confirm the specific markers identified in the initial analysis, associations of significant markers with economic traits were further examined in 228 additional performance-tested purebred pigs. Twenty-five microsatellite markers were significantly associated with either ADG or BFT, and among these, 17 were associated with both traits. The markers with the highest association to ADG were also associated with BFT. Our study reveals that specific markers could be used to predict economic significance, and confirms several quantitative trait loci (QTL) identified in previous studies. However, further analysis with more closely-spaced microsatellite markers is required to refine predictive values for economic traits and positions of QTL that are reliable for actual phenotypic prediction.</description><subject>ADG</subject><subject>Alleles</subject><subject>Animals</subject><subject>BACKFAT</subject><subject>BFT</subject><subject>CARTE GENETIQUE</subject><subject>CERDO</subject><subject>Crosses, Genetic</subject><subject>Economic trait</subject><subject>Female</subject><subject>FORECASTING</subject><subject>GAIN DE POIDS</subject><subject>GANANCIA DE PESO</subject><subject>GENE LOCATION</subject><subject>GENETIC MAPS</subject><subject>Genetic Markers</subject><subject>GENETIC PARAMETERS</subject><subject>Genetic Techniques</subject><subject>Genome</subject><subject>Genotype</subject><subject>LARD DORSAL</subject><subject>LOCALISATION DE GENE</subject><subject>LOCALIZACION DE GENES</subject><subject>Male</subject><subject>MAPAS GENETICOS</subject><subject>Microsatellite marker</subject><subject>Microsatellite Repeats</subject><subject>Models, Genetic</subject><subject>Models, Statistical</subject><subject>PARAMETRE GENETIQUE</subject><subject>PARAMETROS GENETICOS</subject><subject>Phenotype</subject><subject>Polymerase Chain Reaction</subject><subject>PORCIN</subject><subject>QTL</subject><subject>Quantitative Trait Loci</subject><subject>SWINE</subject><subject>TECHNIQUE DE PREVISION</subject><subject>TECNICAS DE PREDICCION</subject><subject>TOCINO DORSAL</subject><subject>WEIGHT GAIN</subject><issn>0916-8818</issn><issn>1348-4400</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtKAzEUQIMoWh8LP0DJSnAxmsdkJlmJiE8KKug6JJk7NXXaqUkq9O-NTtGlWdws7uFwOQgdUnJGWcXOp6E5ozUpqw00oryURVkSsolGRNGqkJLKHbQb45QQzkRVbqMdWpVUCEZH6Pk1Au5bPPMu9NEk6DqfAM9MeIcQcepxAwlcwh9LM08-meQ_AadgfMJd7zz2c7zqw3t88wHwwk_iPtpqTRfhYP3vodeb65eru2L8eHt_dTkunFAqFY0oqaVWCGCNFVJZXvOWWkW5BC6FEQCubWzJG6PACecMt0CEaa1sLQXG99DJ4F2E_mMJMemZjy7fb-bQL6OuasUEV_W_IFWC5Rw8g6cD-J0iBmj1IvhcYqUp0d-hdQ6tf0Jn9ngtXdoZNH_kumwGLgZgGpOZwC9gQvKugx-VYJoNgzH1u3FvJmiYZ8PRYGhNr80k-KgfnhghNcmPS_4FbQSaRg</recordid><startdate>20060401</startdate><enddate>20060401</enddate><creator>Kim, C.W.(Jinju National Univ. (Korea R.))</creator><creator>Hong, Y.H</creator><creator>Yun, S.I</creator><creator>Lee, S.R</creator><creator>Kim, Y.H</creator><creator>Kim, M.S</creator><creator>Chung, K.H</creator><creator>Jung, W.Y</creator><creator>Kwon, E.J</creator><creator>Hwang, S.S</creator><creator>Park, D.H</creator><creator>Cho, K. K</creator><creator>Lee, J.G</creator><creator>Kim, B.W</creator><creator>Kim, J.W</creator><creator>Kang, Y.S</creator><creator>Yeo, J.S</creator><creator>Chang, K.T</creator><general>THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20060401</creationdate><title>Use of microsatellite markers to detect quantitative trait loci in yorkshire pigs</title><author>Kim, C.W.(Jinju National Univ. (Korea R.)) ; Hong, Y.H ; Yun, S.I ; Lee, S.R ; Kim, Y.H ; Kim, M.S ; Chung, K.H ; Jung, W.Y ; Kwon, E.J ; Hwang, S.S ; Park, D.H ; Cho, K. K ; Lee, J.G ; Kim, B.W ; Kim, J.W ; Kang, Y.S ; Yeo, J.S ; Chang, K.T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-d541b1b55e2db589b373f1b9138e385a5eecfdb43da9ec5cca3be05afb8fb1e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>ADG</topic><topic>Alleles</topic><topic>Animals</topic><topic>BACKFAT</topic><topic>BFT</topic><topic>CARTE GENETIQUE</topic><topic>CERDO</topic><topic>Crosses, Genetic</topic><topic>Economic trait</topic><topic>Female</topic><topic>FORECASTING</topic><topic>GAIN DE POIDS</topic><topic>GANANCIA DE PESO</topic><topic>GENE LOCATION</topic><topic>GENETIC MAPS</topic><topic>Genetic Markers</topic><topic>GENETIC PARAMETERS</topic><topic>Genetic Techniques</topic><topic>Genome</topic><topic>Genotype</topic><topic>LARD DORSAL</topic><topic>LOCALISATION DE GENE</topic><topic>LOCALIZACION DE GENES</topic><topic>Male</topic><topic>MAPAS GENETICOS</topic><topic>Microsatellite marker</topic><topic>Microsatellite Repeats</topic><topic>Models, Genetic</topic><topic>Models, Statistical</topic><topic>PARAMETRE GENETIQUE</topic><topic>PARAMETROS GENETICOS</topic><topic>Phenotype</topic><topic>Polymerase Chain Reaction</topic><topic>PORCIN</topic><topic>QTL</topic><topic>Quantitative Trait Loci</topic><topic>SWINE</topic><topic>TECHNIQUE DE PREVISION</topic><topic>TECNICAS DE PREDICCION</topic><topic>TOCINO DORSAL</topic><topic>WEIGHT GAIN</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, C.W.(Jinju National Univ. (Korea R.))</creatorcontrib><creatorcontrib>Hong, Y.H</creatorcontrib><creatorcontrib>Yun, S.I</creatorcontrib><creatorcontrib>Lee, S.R</creatorcontrib><creatorcontrib>Kim, Y.H</creatorcontrib><creatorcontrib>Kim, M.S</creatorcontrib><creatorcontrib>Chung, K.H</creatorcontrib><creatorcontrib>Jung, W.Y</creatorcontrib><creatorcontrib>Kwon, E.J</creatorcontrib><creatorcontrib>Hwang, S.S</creatorcontrib><creatorcontrib>Park, D.H</creatorcontrib><creatorcontrib>Cho, K. K</creatorcontrib><creatorcontrib>Lee, J.G</creatorcontrib><creatorcontrib>Kim, B.W</creatorcontrib><creatorcontrib>Kim, J.W</creatorcontrib><creatorcontrib>Kang, Y.S</creatorcontrib><creatorcontrib>Yeo, J.S</creatorcontrib><creatorcontrib>Chang, K.T</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Reproduction and Development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, C.W.(Jinju National Univ. (Korea R.))</au><au>Hong, Y.H</au><au>Yun, S.I</au><au>Lee, S.R</au><au>Kim, Y.H</au><au>Kim, M.S</au><au>Chung, K.H</au><au>Jung, W.Y</au><au>Kwon, E.J</au><au>Hwang, S.S</au><au>Park, D.H</au><au>Cho, K. K</au><au>Lee, J.G</au><au>Kim, B.W</au><au>Kim, J.W</au><au>Kang, Y.S</au><au>Yeo, J.S</au><au>Chang, K.T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of microsatellite markers to detect quantitative trait loci in yorkshire pigs</atitle><jtitle>Journal of Reproduction and Development</jtitle><addtitle>J. Reprod. Dev.</addtitle><date>2006-04-01</date><risdate>2006</risdate><volume>52</volume><issue>2</issue><spage>229</spage><epage>237</epage><pages>229-237</pages><issn>0916-8818</issn><eissn>1348-4400</eissn><abstract>To identify genetic markers associated with economic traits in pigs, 157 microsatellite markers were examined in Yorkshire pigs. Thirty eight female Yorkshire pigs were initially examined and six of them were selected as progenitors; half were more than 1.5 standard deviations (SD) above the mean for average daily gain (ADG) and backfat thickness (BFT), and the remaining half were more than 1.5 SD below the mean. These pigs were then mated to male Duroc pigs, and 200 F2 pig offspring were examined for the association of specific alleles with ADG and BFT. To confirm the specific markers identified in the initial analysis, associations of significant markers with economic traits were further examined in 228 additional performance-tested purebred pigs. Twenty-five microsatellite markers were significantly associated with either ADG or BFT, and among these, 17 were associated with both traits. The markers with the highest association to ADG were also associated with BFT. Our study reveals that specific markers could be used to predict economic significance, and confirms several quantitative trait loci (QTL) identified in previous studies. However, further analysis with more closely-spaced microsatellite markers is required to refine predictive values for economic traits and positions of QTL that are reliable for actual phenotypic prediction.</abstract><cop>Japan</cop><pub>THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</pub><pmid>16415521</pmid><doi>10.1262/jrd.17046</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of Reproduction and Development, 2006, Vol.52(2), pp.229-237 |
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| source | J-STAGE (Free - Japanese); MEDLINE; EZB-FREE-00999 freely available EZB journals; Directory of Open Access Journals; AgriKnowledge（アグリナレッジ）AGROLib |
| subjects | ADG Alleles Animals BACKFAT BFT CARTE GENETIQUE CERDO Crosses, Genetic Economic trait Female FORECASTING GAIN DE POIDS GANANCIA DE PESO GENE LOCATION GENETIC MAPS Genetic Markers GENETIC PARAMETERS Genetic Techniques Genome Genotype LARD DORSAL LOCALISATION DE GENE LOCALIZACION DE GENES Male MAPAS GENETICOS Microsatellite marker Microsatellite Repeats Models, Genetic Models, Statistical PARAMETRE GENETIQUE PARAMETROS GENETICOS Phenotype Polymerase Chain Reaction PORCIN QTL Quantitative Trait Loci SWINE TECHNIQUE DE PREVISION TECNICAS DE PREDICCION TOCINO DORSAL WEIGHT GAIN |
| title | Use of microsatellite markers to detect quantitative trait loci in yorkshire pigs |
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