An immunocytometric assay based on dengue infection via DC-SIGN permits rapid measurement of anti-dengue neutralizing antibodies

Dengue remains a global public health threat and development of a safe and effective vaccine is a principal public health goal. The primary correlate of immunity is thought to be neutralizing antibodies. Currently, the plaque reduction neutralization test (PRNT) is the gold standard measure of dengu...

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Veröffentlicht in:Journal of virological methods 2006-06, Vol.134 (1), p.74-85
Hauptverfasser: Martin, Nicole C., Pardo, Jorge, Simmons, Monika, Tjaden, Jeffrey A., Widjaja, Susana, Marovich, Mary A., Sun, Wellington, Porter, Kevin R., Burgess, Timothy H.
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Sprache:eng
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