IPPB-assisted coughing in neuromuscular disorders
In neuromuscular disorders, reduced peak cough flows (PCFs) are considered to increase the risk of respiratory complications such as pneumonia or chronic atelectasis. Different methods were described to improve PCF. However, these studies were primarily carried out in adults, and there is limited in...
Gespeichert in:
| Veröffentlicht in: | Pediatric pulmonology 2006-06, Vol.41 (6), p.551-557 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 557 |
|---|---|
| container_issue | 6 |
| container_start_page | 551 |
| container_title | Pediatric pulmonology |
| container_volume | 41 |
| creator | Dohna-Schwake, Christian Ragette, Regine Teschler, Helmut Voit, Thomas Mellies, Uwe |
| description | In neuromuscular disorders, reduced peak cough flows (PCFs) are considered to increase the risk of respiratory complications such as pneumonia or chronic atelectasis. Different methods were described to improve PCF. However, these studies were primarily carried out in adults, and there is limited information regarding the use and efficacy of these methods in children with respiratory muscle weakness. The aim of this study was to investigate whether hyperinsufflation with an intermittent positive‐pressure breathing (IPPB) device is effective in cough augmentation in pediatric patients. Spirometry (forced inspiratory vital capacity, FIVC; forced expiratory volume in 1 sec, FEV1), respiratory muscle pressures (peak inspiratory pressure, PIP; peak expiratory pressure, PEP), and PCF were measured in 29 schoolchildren with various neuromuscular disorders. IPPB‐assisted hyperinsufflation was taught individually to increase lung volumes (maximum insufflation capacity, MIC) above FIVC. The impact of hyperinsufflation on peak cough flow was documented. In 28/29 patients, IPPB‐assisted hyperinsufflation enhanced FIVC from 0.68 ± 0.40 l to an MIC of 1.05 ± 0.47 l (P |
| doi_str_mv | 10.1002/ppul.20406 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67924299</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67924299</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4616-edd4fee90e23d22c0d5cf624fad6b66f183336e445be738fd2810a026a14e6773</originalsourceid><addsrcrecordid>eNp9kD1PwzAQhi0EgvKx8ANQFxiQAj7bOScjRVBAFVQCxGi59gUCaVJsIuDfk9ICG9MN97zv6R7GdoEfAefieDZrqyPBFccV1gOe5wlXOa6yXqbTNMEM5QbbjPGZ826XwzrbAETQKoUeg8vxeJDYGMv4Rr7vmvbxqawf-2Xdr6kNzbSNrq1s6PsyNsFTiNtsrbBVpJ3l3GL352d3pxfJ6GZ4eXoySpxCwIS8VwVRzklIL4TjPnUFClVYjxPEAjIpJZJS6YS0zAovMuCWC7SgCLWWW-xg0TsLzWtL8c1My-ioqmxNTRsN6lwokecdeLgAXWhiDFSYWSinNnwa4GYuyMwFmW9BHby3bG0nU_J_6NJIB-wvARudrYpga1fGP05noAHnHCy497Kiz39OmvH4fvRzPFlk5rI_fjM2vHTfSJ2ah-uh4VfiDmFwa4byCxzBi-E</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67924299</pqid></control><display><type>article</type><title>IPPB-assisted coughing in neuromuscular disorders</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Dohna-Schwake, Christian ; Ragette, Regine ; Teschler, Helmut ; Voit, Thomas ; Mellies, Uwe</creator><creatorcontrib>Dohna-Schwake, Christian ; Ragette, Regine ; Teschler, Helmut ; Voit, Thomas ; Mellies, Uwe</creatorcontrib><description>In neuromuscular disorders, reduced peak cough flows (PCFs) are considered to increase the risk of respiratory complications such as pneumonia or chronic atelectasis. Different methods were described to improve PCF. However, these studies were primarily carried out in adults, and there is limited information regarding the use and efficacy of these methods in children with respiratory muscle weakness. The aim of this study was to investigate whether hyperinsufflation with an intermittent positive‐pressure breathing (IPPB) device is effective in cough augmentation in pediatric patients. Spirometry (forced inspiratory vital capacity, FIVC; forced expiratory volume in 1 sec, FEV1), respiratory muscle pressures (peak inspiratory pressure, PIP; peak expiratory pressure, PEP), and PCF were measured in 29 schoolchildren with various neuromuscular disorders. IPPB‐assisted hyperinsufflation was taught individually to increase lung volumes (maximum insufflation capacity, MIC) above FIVC. The impact of hyperinsufflation on peak cough flow was documented. In 28/29 patients, IPPB‐assisted hyperinsufflation enhanced FIVC from 0.68 ± 0.40 l to an MIC of 1.05 ± 0.47 l (P < 0.001). Unassisted PCF was 119.0 ± 57.7 l/min, and increased to 194.5 ± 74.9 l/min (P < 0.001) in 27/29 patients. This effect was similar in young patients (ages 6–10 years) and older patients (aged >10 years). Augmentation of lung volumes from FIVC to MIC correlated with an increase of PCF (R = 0.42, P < 0.05). IPPB‐assisted hyperinsufflation improves PCF in pediatric neuromuscular disorders. The results suggest that this technique can be used to improve clearance of airway secretions and therefore reduce respiratory morbidity in children with NMD. Pediatr Pulmonol. © 2006 Wiley‐Liss, Inc.</description><identifier>ISSN: 8755-6863</identifier><identifier>EISSN: 1099-0496</identifier><identifier>DOI: 10.1002/ppul.20406</identifier><identifier>PMID: 16617451</identifier><identifier>CODEN: PEPUES</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Age Factors ; assisted coughing ; Biological and medical sciences ; Child ; Cough - etiology ; Cough - therapy ; Female ; Forced Expiratory Volume - physiology ; Humans ; Intermittent Positive-Pressure Breathing - methods ; Male ; maximum insufflation capacity ; Medical sciences ; Muscle Weakness - physiopathology ; Muscular Atrophy, Spinal - complications ; Muscular Atrophy, Spinal - physiopathology ; Muscular Dystrophies - complications ; Muscular Dystrophies - congenital ; Muscular Dystrophies - physiopathology ; Muscular Dystrophy, Duchenne - complications ; Muscular Dystrophy, Duchenne - physiopathology ; Neuromuscular Diseases - complications ; Neuromuscular Diseases - physiopathology ; neuromuscular disorders ; peak cough flow ; Pneumology ; Pulmonary Ventilation - physiology ; Respiration Disorders - etiology ; Respiration Disorders - therapy ; Respiratory Function Tests ; respiratory muscle weakness ; Respiratory Muscles - physiopathology ; Respiratory system : syndromes and miscellaneous diseases ; Respiratory Therapy - instrumentation ; Respiratory Therapy - methods ; Spirometry ; Treatment Outcome ; Vital Capacity - physiology</subject><ispartof>Pediatric pulmonology, 2006-06, Vol.41 (6), p.551-557</ispartof><rights>Copyright © 2006 Wiley‐Liss, Inc.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright 2006 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4616-edd4fee90e23d22c0d5cf624fad6b66f183336e445be738fd2810a026a14e6773</citedby><cites>FETCH-LOGICAL-c4616-edd4fee90e23d22c0d5cf624fad6b66f183336e445be738fd2810a026a14e6773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fppul.20406$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fppul.20406$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17817161$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16617451$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dohna-Schwake, Christian</creatorcontrib><creatorcontrib>Ragette, Regine</creatorcontrib><creatorcontrib>Teschler, Helmut</creatorcontrib><creatorcontrib>Voit, Thomas</creatorcontrib><creatorcontrib>Mellies, Uwe</creatorcontrib><title>IPPB-assisted coughing in neuromuscular disorders</title><title>Pediatric pulmonology</title><addtitle>Pediatr. Pulmonol</addtitle><description>In neuromuscular disorders, reduced peak cough flows (PCFs) are considered to increase the risk of respiratory complications such as pneumonia or chronic atelectasis. Different methods were described to improve PCF. However, these studies were primarily carried out in adults, and there is limited information regarding the use and efficacy of these methods in children with respiratory muscle weakness. The aim of this study was to investigate whether hyperinsufflation with an intermittent positive‐pressure breathing (IPPB) device is effective in cough augmentation in pediatric patients. Spirometry (forced inspiratory vital capacity, FIVC; forced expiratory volume in 1 sec, FEV1), respiratory muscle pressures (peak inspiratory pressure, PIP; peak expiratory pressure, PEP), and PCF were measured in 29 schoolchildren with various neuromuscular disorders. IPPB‐assisted hyperinsufflation was taught individually to increase lung volumes (maximum insufflation capacity, MIC) above FIVC. The impact of hyperinsufflation on peak cough flow was documented. In 28/29 patients, IPPB‐assisted hyperinsufflation enhanced FIVC from 0.68 ± 0.40 l to an MIC of 1.05 ± 0.47 l (P < 0.001). Unassisted PCF was 119.0 ± 57.7 l/min, and increased to 194.5 ± 74.9 l/min (P < 0.001) in 27/29 patients. This effect was similar in young patients (ages 6–10 years) and older patients (aged >10 years). Augmentation of lung volumes from FIVC to MIC correlated with an increase of PCF (R = 0.42, P < 0.05). IPPB‐assisted hyperinsufflation improves PCF in pediatric neuromuscular disorders. The results suggest that this technique can be used to improve clearance of airway secretions and therefore reduce respiratory morbidity in children with NMD. Pediatr Pulmonol. © 2006 Wiley‐Liss, Inc.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>assisted coughing</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Cough - etiology</subject><subject>Cough - therapy</subject><subject>Female</subject><subject>Forced Expiratory Volume - physiology</subject><subject>Humans</subject><subject>Intermittent Positive-Pressure Breathing - methods</subject><subject>Male</subject><subject>maximum insufflation capacity</subject><subject>Medical sciences</subject><subject>Muscle Weakness - physiopathology</subject><subject>Muscular Atrophy, Spinal - complications</subject><subject>Muscular Atrophy, Spinal - physiopathology</subject><subject>Muscular Dystrophies - complications</subject><subject>Muscular Dystrophies - congenital</subject><subject>Muscular Dystrophies - physiopathology</subject><subject>Muscular Dystrophy, Duchenne - complications</subject><subject>Muscular Dystrophy, Duchenne - physiopathology</subject><subject>Neuromuscular Diseases - complications</subject><subject>Neuromuscular Diseases - physiopathology</subject><subject>neuromuscular disorders</subject><subject>peak cough flow</subject><subject>Pneumology</subject><subject>Pulmonary Ventilation - physiology</subject><subject>Respiration Disorders - etiology</subject><subject>Respiration Disorders - therapy</subject><subject>Respiratory Function Tests</subject><subject>respiratory muscle weakness</subject><subject>Respiratory Muscles - physiopathology</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Respiratory Therapy - instrumentation</subject><subject>Respiratory Therapy - methods</subject><subject>Spirometry</subject><subject>Treatment Outcome</subject><subject>Vital Capacity - physiology</subject><issn>8755-6863</issn><issn>1099-0496</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EgvKx8ANQFxiQAj7bOScjRVBAFVQCxGi59gUCaVJsIuDfk9ICG9MN97zv6R7GdoEfAefieDZrqyPBFccV1gOe5wlXOa6yXqbTNMEM5QbbjPGZ826XwzrbAETQKoUeg8vxeJDYGMv4Rr7vmvbxqawf-2Xdr6kNzbSNrq1s6PsyNsFTiNtsrbBVpJ3l3GL352d3pxfJ6GZ4eXoySpxCwIS8VwVRzklIL4TjPnUFClVYjxPEAjIpJZJS6YS0zAovMuCWC7SgCLWWW-xg0TsLzWtL8c1My-ioqmxNTRsN6lwokecdeLgAXWhiDFSYWSinNnwa4GYuyMwFmW9BHby3bG0nU_J_6NJIB-wvARudrYpga1fGP05noAHnHCy497Kiz39OmvH4fvRzPFlk5rI_fjM2vHTfSJ2ah-uh4VfiDmFwa4byCxzBi-E</recordid><startdate>200606</startdate><enddate>200606</enddate><creator>Dohna-Schwake, Christian</creator><creator>Ragette, Regine</creator><creator>Teschler, Helmut</creator><creator>Voit, Thomas</creator><creator>Mellies, Uwe</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200606</creationdate><title>IPPB-assisted coughing in neuromuscular disorders</title><author>Dohna-Schwake, Christian ; Ragette, Regine ; Teschler, Helmut ; Voit, Thomas ; Mellies, Uwe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4616-edd4fee90e23d22c0d5cf624fad6b66f183336e445be738fd2810a026a14e6773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>assisted coughing</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Cough - etiology</topic><topic>Cough - therapy</topic><topic>Female</topic><topic>Forced Expiratory Volume - physiology</topic><topic>Humans</topic><topic>Intermittent Positive-Pressure Breathing - methods</topic><topic>Male</topic><topic>maximum insufflation capacity</topic><topic>Medical sciences</topic><topic>Muscle Weakness - physiopathology</topic><topic>Muscular Atrophy, Spinal - complications</topic><topic>Muscular Atrophy, Spinal - physiopathology</topic><topic>Muscular Dystrophies - complications</topic><topic>Muscular Dystrophies - congenital</topic><topic>Muscular Dystrophies - physiopathology</topic><topic>Muscular Dystrophy, Duchenne - complications</topic><topic>Muscular Dystrophy, Duchenne - physiopathology</topic><topic>Neuromuscular Diseases - complications</topic><topic>Neuromuscular Diseases - physiopathology</topic><topic>neuromuscular disorders</topic><topic>peak cough flow</topic><topic>Pneumology</topic><topic>Pulmonary Ventilation - physiology</topic><topic>Respiration Disorders - etiology</topic><topic>Respiration Disorders - therapy</topic><topic>Respiratory Function Tests</topic><topic>respiratory muscle weakness</topic><topic>Respiratory Muscles - physiopathology</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Respiratory Therapy - instrumentation</topic><topic>Respiratory Therapy - methods</topic><topic>Spirometry</topic><topic>Treatment Outcome</topic><topic>Vital Capacity - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dohna-Schwake, Christian</creatorcontrib><creatorcontrib>Ragette, Regine</creatorcontrib><creatorcontrib>Teschler, Helmut</creatorcontrib><creatorcontrib>Voit, Thomas</creatorcontrib><creatorcontrib>Mellies, Uwe</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric pulmonology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dohna-Schwake, Christian</au><au>Ragette, Regine</au><au>Teschler, Helmut</au><au>Voit, Thomas</au><au>Mellies, Uwe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IPPB-assisted coughing in neuromuscular disorders</atitle><jtitle>Pediatric pulmonology</jtitle><addtitle>Pediatr. Pulmonol</addtitle><date>2006-06</date><risdate>2006</risdate><volume>41</volume><issue>6</issue><spage>551</spage><epage>557</epage><pages>551-557</pages><issn>8755-6863</issn><eissn>1099-0496</eissn><coden>PEPUES</coden><abstract>In neuromuscular disorders, reduced peak cough flows (PCFs) are considered to increase the risk of respiratory complications such as pneumonia or chronic atelectasis. Different methods were described to improve PCF. However, these studies were primarily carried out in adults, and there is limited information regarding the use and efficacy of these methods in children with respiratory muscle weakness. The aim of this study was to investigate whether hyperinsufflation with an intermittent positive‐pressure breathing (IPPB) device is effective in cough augmentation in pediatric patients. Spirometry (forced inspiratory vital capacity, FIVC; forced expiratory volume in 1 sec, FEV1), respiratory muscle pressures (peak inspiratory pressure, PIP; peak expiratory pressure, PEP), and PCF were measured in 29 schoolchildren with various neuromuscular disorders. IPPB‐assisted hyperinsufflation was taught individually to increase lung volumes (maximum insufflation capacity, MIC) above FIVC. The impact of hyperinsufflation on peak cough flow was documented. In 28/29 patients, IPPB‐assisted hyperinsufflation enhanced FIVC from 0.68 ± 0.40 l to an MIC of 1.05 ± 0.47 l (P < 0.001). Unassisted PCF was 119.0 ± 57.7 l/min, and increased to 194.5 ± 74.9 l/min (P < 0.001) in 27/29 patients. This effect was similar in young patients (ages 6–10 years) and older patients (aged >10 years). Augmentation of lung volumes from FIVC to MIC correlated with an increase of PCF (R = 0.42, P < 0.05). IPPB‐assisted hyperinsufflation improves PCF in pediatric neuromuscular disorders. The results suggest that this technique can be used to improve clearance of airway secretions and therefore reduce respiratory morbidity in children with NMD. Pediatr Pulmonol. © 2006 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>16617451</pmid><doi>10.1002/ppul.20406</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 8755-6863 |
| ispartof | Pediatric pulmonology, 2006-06, Vol.41 (6), p.551-557 |
| issn | 8755-6863 1099-0496 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67924299 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Age Factors assisted coughing Biological and medical sciences Child Cough - etiology Cough - therapy Female Forced Expiratory Volume - physiology Humans Intermittent Positive-Pressure Breathing - methods Male maximum insufflation capacity Medical sciences Muscle Weakness - physiopathology Muscular Atrophy, Spinal - complications Muscular Atrophy, Spinal - physiopathology Muscular Dystrophies - complications Muscular Dystrophies - congenital Muscular Dystrophies - physiopathology Muscular Dystrophy, Duchenne - complications Muscular Dystrophy, Duchenne - physiopathology Neuromuscular Diseases - complications Neuromuscular Diseases - physiopathology neuromuscular disorders peak cough flow Pneumology Pulmonary Ventilation - physiology Respiration Disorders - etiology Respiration Disorders - therapy Respiratory Function Tests respiratory muscle weakness Respiratory Muscles - physiopathology Respiratory system : syndromes and miscellaneous diseases Respiratory Therapy - instrumentation Respiratory Therapy - methods Spirometry Treatment Outcome Vital Capacity - physiology |
| title | IPPB-assisted coughing in neuromuscular disorders |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T00%3A47%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=IPPB-assisted%20coughing%20in%20neuromuscular%20disorders&rft.jtitle=Pediatric%20pulmonology&rft.au=Dohna-Schwake,%20Christian&rft.date=2006-06&rft.volume=41&rft.issue=6&rft.spage=551&rft.epage=557&rft.pages=551-557&rft.issn=8755-6863&rft.eissn=1099-0496&rft.coden=PEPUES&rft_id=info:doi/10.1002/ppul.20406&rft_dat=%3Cproquest_cross%3E67924299%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67924299&rft_id=info:pmid/16617451&rfr_iscdi=true |