Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review

One of the most prominent neuropsychologic theories of attention-deficit/hyperactivity disorder (ADHD) suggests that its symptoms arise from a primary deficit in executive functions (EF), defined as neurocognitive processes that maintain an appropriate problem-solving set to attain a later goal. To...

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Veröffentlicht in:Biological psychiatry (1969) 2005-06, Vol.57 (11), p.1336-1346
Hauptverfasser: Willcutt, Erik G., Doyle, Alysa E., Nigg, Joel T., Faraone, Stephen V., Pennington, Bruce F.
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container_end_page 1346
container_issue 11
container_start_page 1336
container_title Biological psychiatry (1969)
container_volume 57
creator Willcutt, Erik G.
Doyle, Alysa E.
Nigg, Joel T.
Faraone, Stephen V.
Pennington, Bruce F.
description One of the most prominent neuropsychologic theories of attention-deficit/hyperactivity disorder (ADHD) suggests that its symptoms arise from a primary deficit in executive functions (EF), defined as neurocognitive processes that maintain an appropriate problem-solving set to attain a later goal. To examine the validity of the EF theory, we conducted a meta-analysis of 83 studies that administered EF measures to groups with ADHD (total N = 3734) and without ADHD ( N = 2969). Groups with ADHD exhibited significant impairment on all EF tasks. Effect sizes for all measures fell in the medium range (.46–.69), but the strongest and most consistent effects were obtained on measures of response inhibition, vigilance, working memory, and planning. Weaknesses in EF were significant in both clinic-referred and community samples and were not explained by group differences in intelligence, academic achievement, or symptoms of other disorders. ADHD is associated with significant weaknesses in several key EF domains. However, moderate effect sizes and lack of universality of EF deficits among individuals with ADHD suggest that EF weaknesses are neither necessary nor sufficient to cause all cases of ADHD. Difficulties with EF appear to be one important component of the complex neuropsychology of ADHD.
doi_str_mv 10.1016/j.biopsych.2005.02.006
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subjects Algorithms
Attention Deficit Disorder with Hyperactivity - physiopathology
Attention deficit disorders. Hyperactivity
Attention-deficit/hyperactivity disorder
Biological and medical sciences
Child clinical studies
Cognition - physiology
Cognition Disorders - etiology
executive function
Humans
Medical sciences
meta-analysis
Models, Psychological
Neuropsychological Tests
neuropsychology
Problem Solving - physiology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Reproducibility of Results
subtypes
title Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review
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