A study to determine the effect of tacrolimus on ceramide levels in the stratum corneum of patients with atopic dermatitis

Background Atopic dermatitis (AD) is characterized both by inflammation and by abnormally low ceramide levels in the stratum corneum. Tacrolimus, effective in the treatment of AD, inhibits transcription and release of inflammatory cytokines operative in AD, but it is unknown if tacrolimus normalize...

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Veröffentlicht in:	International journal of dermatology 2006-04, Vol.45 (4), p.352-356
Hauptverfasser:	Paslin, David, Wertz, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergic diseases Biological and medical sciences Ceramides - metabolism Dermatitis, Atopic - drug therapy Dermatitis, Atopic - metabolism Dermatology Female Humans Immunopathology Immunosuppressive Agents - therapeutic use Male Medical sciences Middle Aged Ointments Pilot Projects Reference Values Skin - metabolism Skin allergic diseases. Stinging insect allergies Tacrolimus - therapeutic use
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