Follicular Cells Acquire Sertoli Cell Characteristics after Oocyte Loss

Although it has been suggested that in mammals the loss of female germ cells may induce the masculinization of the ovarian compartment, there has been as yet no conclusive demonstration. To directly address that question, the present study has been designed to determine the fate of follicular cells...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2005-07, Vol.146 (7), p.2992-3004
Hauptverfasser:	Guigon, Céline J, Coudouel, Noëlline, Mazaud-Guittot, Séverine, Forest, Maguelone G, Magre, Solange
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Mullerian Hormone Biological and medical sciences Biomarkers - metabolism Cell Differentiation - physiology Cell junctions Cell Survival - physiology Cytoplasm Depletion DNA-Binding Proteins - metabolism Female Females Follicle Stimulating Hormone - blood Follicle-stimulating hormone Follicles Forkhead protein Fundamental and applied biological sciences. Psychology Gametocytes Gamma irradiation Gamma Rays Germ cells Glycoproteins - metabolism Granulosa cells Granulosa Cells - physiology Inhibin Inhibins - metabolism Irradiation Maintenance Male Oocytes Oocytes - cytology Oocytes - radiation effects Ovarian Follicle - cytology Ovarian Follicle - metabolism Ovarian Follicle - physiology Phenotype Phenotypes Physical characteristics Rats Sertoli cells Sertoli Cells - cytology Sertoli Cells - physiology Testicular Hormones - metabolism Transcription Factors - metabolism Vertebrates: endocrinology γ Radiation
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