Global gene expression profiles associated with retinoic acid-induced differentiation of embryonal carcinoma cells

We have evaluated the effects of retinoic acid (RA) treatment of F9 embryonal carcinoma (EC) cells, which induces differentiation into primitive endoderm, on gene expression patterns. F9 cells were exposed to RA in culture, and global expression patterns were examined with cDNA‐based microarrays at...

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Veröffentlicht in:	Molecular reproduction and development 2006-07, Vol.73 (7), p.796-824
Hauptverfasser:	Eifert, Cheryl, Sangster-Guity, Niquiche, Yu, Li-Ming, Chittur, Sridar V., Perez, Ana V., Tine, John A., McCormick, Paulette J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Biological and medical sciences Cell Differentiation - drug effects Cell Differentiation - genetics Cell Line, Tumor Cell Proliferation - drug effects differentiation Down-Regulation - drug effects embryonal carcinoma Embryonal Carcinoma Stem Cells Endoderm gene expression profiles Gene Expression Profiling Gene Expression Regulation, Developmental - drug effects Medical sciences Mice microarray Neoplastic Stem Cells - cytology Neoplastic Stem Cells - drug effects Oligonucleotide Array Sequence Analysis retinoic acid Spontaneous animal tumors Tretinoin - pharmacology Tumors Up-Regulation - drug effects
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