Epilepsia partialis continua in a patient with Behçet's disease
Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder of unknown aetiology. Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seiz...
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| Veröffentlicht in: | Clinical neurology and neurosurgery 2006-06, Vol.108 (4), p.392-395 |
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| creator | Aktekin, Berrin Doğan, Ebru Apaydın Oğuz, Yurttaş Karaali, Kamil |
| description | Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder of unknown aetiology. Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate. |
| doi_str_mv | 10.1016/j.clineuro.2004.12.021 |
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Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate.</description><identifier>ISSN: 0303-8467</identifier><identifier>EISSN: 1872-6968</identifier><identifier>DOI: 10.1016/j.clineuro.2004.12.021</identifier><identifier>PMID: 16644404</identifier><identifier>CODEN: CNNSBV</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adult ; Anti-Inflammatory Agents - therapeutic use ; Behcet Syndrome - complications ; Behcet Syndrome - diagnosis ; Behcet Syndrome - drug therapy ; Behçet's disease ; Biological and medical sciences ; Brain - pathology ; Brain - physiopathology ; Electroencephalography ; Epilepsia partialis continua ; Epilepsies, Partial - complications ; Epilepsies, Partial - diagnosis ; Epilepsies, Partial - physiopathology ; Female ; Humans ; Magnetic Resonance Imaging ; Medical sciences ; Methylprednisolone - therapeutic use ; Neurological involvement ; Neurology ; Neurosurgery ; Periodicity ; Recurrence ; Seizure ; Surgery (general aspects). 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Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate.</description><subject>Adult</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Behcet Syndrome - complications</subject><subject>Behcet Syndrome - diagnosis</subject><subject>Behcet Syndrome - drug therapy</subject><subject>Behçet's disease</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Brain - physiopathology</subject><subject>Electroencephalography</subject><subject>Epilepsia partialis continua</subject><subject>Epilepsies, Partial - complications</subject><subject>Epilepsies, Partial - diagnosis</subject><subject>Epilepsies, Partial - physiopathology</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Methylprednisolone - therapeutic use</subject><subject>Neurological involvement</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Periodicity</subject><subject>Recurrence</subject><subject>Seizure</subject><subject>Surgery (general aspects). 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| subjects | Adult Anti-Inflammatory Agents - therapeutic use Behcet Syndrome - complications Behcet Syndrome - diagnosis Behcet Syndrome - drug therapy Behçet's disease Biological and medical sciences Brain - pathology Brain - physiopathology Electroencephalography Epilepsia partialis continua Epilepsies, Partial - complications Epilepsies, Partial - diagnosis Epilepsies, Partial - physiopathology Female Humans Magnetic Resonance Imaging Medical sciences Methylprednisolone - therapeutic use Neurological involvement Neurology Neurosurgery Periodicity Recurrence Seizure Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases |
| title | Epilepsia partialis continua in a patient with Behçet's disease |
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