Relation between Polymorphisms G1704T and G82S of RAGE Gene and Diabetic Retinopathy in Japanese Type 2 Diabetic Patients

Objective To clarify whether polymorphisms G1704T and G82S of the RAGE gene were related to diabetic retinopathy, we performed a case-control study in Japanese type 2 diabetic patients. Patients and Methods Two hundred and sixty-eight patients with type 2 diabetes were examined for polymorphisms G17...

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Veröffentlicht in:	Internal Medicine 2005, Vol.44(5), pp.417-421
Hauptverfasser:	YOSHIOKA, Keiji, YOSHIDA, Toshihide, TAKAKURA, Yasuto, UMEKAWA, Tsunekazu, KOGURE, Akinori, TODA, Hitoshi, YOSHIKAWA, Toshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Alleles Biological and medical sciences Case-Control Studies Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance diabetic retinopathy Diabetic Retinopathy - epidemiology Diabetic Retinopathy - etiology Diabetic Retinopathy - genetics Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Gene Frequency General aspects Genetic Markers - genetics Genotype Glycated Hemoglobin A - metabolism Humans Japan - epidemiology Lipids - blood Male Medical sciences Middle Aged Polymerase Chain Reaction Polymorphism, Single Nucleotide Prevalence RAGE gene Receptor for Advanced Glycation End Products Receptors, Immunologic - genetics Risk Factors single nucleotide polymorphism (SNP)
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