Multi-SNP analysis of MHC region : Remarkable conservation of HLA-A1-B8-DR3 haplotype

Technology has become available to cost-effectively analyze thousands of single nucleotide polymorphisms (SNPs). We recently confirmed by genotyping a small series of class I alleles and microsatellite markers that the extended haplotype HLA-A1-B8-DR3 (8.1 AH) at the major histocompatibility complex...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2006-05, Vol.55 (5), p.1265-1269
Hauptverfasser:	ALY, Theresa A, ELLER, Elise, IDE, Akane, GOWAN, Katherine, BABU, Sunanda R, ERLICH, Henry A, REWERS, Marian J, EISENBARTH, George S, FAIN, Pamela R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Diabetes Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Diabetes research Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genes Genetic Predisposition to Disease Genetic testing Haplotypes HLA-A1 Antigen - genetics HLA-B8 Antigen - genetics HLA-DR3 Antigen - genetics Homozygote Humans Major Histocompatibility Complex Medical sciences Polymorphism, Single Nucleotide Reproducibility Single nucleotide polymorphisms
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!