Protective Effect of the HLA-Bw4I80 Epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 Gene against the Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection

The aim of the present study was to investigate, in 152 Spanish patients infected with hepatitis C virus (HCV), the possibility that killer cell immunoglobulin-like receptors (KIRs) influence progression to hepatocellular carcinoma. KIRs are related to the activation and inhibition of natural killer...

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Veröffentlicht in:	The Journal of infectious diseases 2005-07, Vol.192 (1), p.162-165
Hauptverfasser:	López-Vázquez, Antonio, Rodrigo, Luis, Martínez-Borra, Jesús, Pérez, Ramón, Rodríguez, Manuel, Fdez-Morera, Juan L., Fuentes, Dolores, Rodríguez-Rodero, Sandra, González, Segundo, López-Larrea, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Biological and medical sciences Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - immunology Disease Progression Epitopes Epitopes - genetics Female Fundamental and applied biological sciences. Psychology Genotype Hepacivirus Hepatitis C - genetics Hepatitis C - immunology Hepatitis C virus Hepatocellular carcinoma HLA-B Antigens - genetics Human viral diseases Humans Infections Infectious diseases Killer Cells, Natural - immunology Liver cirrhosis Liver Cirrhosis - immunology Male Medical sciences Microbiology Middle Aged Molecules Natural killer cells Receptors Receptors, Immunologic - genetics Receptors, KIR Receptors, KIR3DS1 T lymphocytes Tumors Viral diseases Viral hepatitis Viruses
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