Prostaglandin, leukotriene, and lipoxin balance in chronic rhinosinusitis with and without nasal polyposis

Upper airway diseases and especially the aspirin hypersensitivity syndrome have been linked to changes in the arachidonic acid cascade; however, the specificity of these changes and their relation to inflammatory reactions in these diseases still remain controversial. We aimed to study the tissue ei...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2005-06, Vol.115 (6), p.1189-1196
Hauptverfasser:	Pérez-Novo, Claudina Angela, Watelet, Jean Baptiste, Claeys, Cindy, Van Cauwenberge, Paul, Bachert, Claus
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arachidonate 5-Lipoxygenase - genetics Arachidonate 5-Lipoxygenase - metabolism Aspirin aspirin sensitivity Biological and medical sciences Chronic Disease Chronic rhinosinusitis cyclooxygenase Cyclooxygenase 2 Cysts Disease Eicosanoids - metabolism Enzymes Eosinophil Cationic Protein - analysis Family medical history Female Fundamental and applied biological sciences. Psychology Fundamental immunology Glutathione Transferase - genetics Glutathione Transferase - metabolism Hospitals Humans Immunopathology inflammation Interleukin-5 - analysis leukotrienes Leukotrienes - metabolism lipoxins Lipoxins - analysis Lipoxins - metabolism lipoxygenase Male Medical imaging Medical sciences Membrane Proteins Middle Aged Nasal Mucosa - immunology Nasal Mucosa - metabolism nasal polyposis Nasal Polyps - complications Nasal Polyps - metabolism Nose Polymerase Chain Reaction Prostaglandin-Endoperoxide Synthases - genetics Prostaglandin-Endoperoxide Synthases - metabolism prostaglandins Prostaglandins - metabolism Rhinitis - complications Rhinitis - metabolism RNA, Messenger - metabolism Sinuses Sinusitis - complications Sinusitis - metabolism Studies Surgery
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