Model‐based analysis of trial data: microfilaria and worm‐productivity loss after diethylcarbamazine–albendazole or ivermectin–albendazole combination therapy against Wuchereria bancrofti

Summary Objectives To determine the efficacies of combinations of ivermectin or diethylcarbamazine and albendazole, which are recommended for use in mass treatment programmes against lymphatic filariasis. Method Review of published trends in microfilarial (mf) intensities after treatment with thes...

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Veröffentlicht in:	Tropical medicine & international health 2006-05, Vol.11 (5), p.718-728
Hauptverfasser:	De Kraker, Marlieke E. A., Stolk, Wilma A., Van Oortmarssen, Gerrit J., Habbema, J. Dik F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged albendazol albendazole Albendazole - administration & dosage Albendazole - therapeutic use Animals Anthelmintics - administration & dosage Anthelmintics - therapeutic use Antiparasitic Agents - administration & dosage Antiparasitic Agents - therapeutic use Biological and medical sciences Child Clinical trials diethylcarbamazine Diethylcarbamazine - administration & dosage Diethylcarbamazine - therapeutic use dietilcarbamazina Diseases caused by nematodes Drug therapy Drug Therapy, Combination efficacité du traitement Elephantiasis, Filarial - drug therapy Filariases filariasis linfática Filaricides - administration & dosage Filaricides - therapeutic use filariose lymphatique General aspects Helminthic diseases Humans Infectious diseases ivermectin Ivermectin - administration & dosage Ivermectin - therapeutic use ivermectina Longevity Lymphatic filariases lymphatic filariasis Mathematical models Medical sciences Microfilariae - drug effects Microfilariae - growth & development Middle Aged Models, Statistical Parasitic diseases Randomized Controlled Trials as Topic Research Design tratamiento eficacia treatment efficacy Treatment Outcome Wuchereria bancrofti Wuchereria bancrofti - drug effects Wuchereria bancrofti - growth & development
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