Evidence for Resonance Optical Trapping of Individual Fluorophore-Labeled Antibodies Using Single Molecule Fluorescence Spectroscopy

We report single molecule fluorescence studies of the diffusion of individual multiple fluorophore-labeled antibodies in solution, which show that a trapping potential of about 3.6 k B T can be obtained at laser powers below 1 mW with resonant excitation. Individual antibodies can be trapped for up...

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Veröffentlicht in:	Journal of the American Chemical Society 2006-05, Vol.128 (17), p.5711-5717
Hauptverfasser:	Li, Haitao, Zhou, Dejian, Browne, Helena, Klenerman, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - chemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Molecular biophysics Optics and Photonics Photochemistry. Photosynthesis. Bioluminescence Radiation-biomolecule interaction Spectrometry, Fluorescence - methods
Online-Zugang:	Volltext
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