The HIV coreceptor switch: a population dynamical perspective

Over the course of infection, the coreceptor usage of the HIV virus changes from a preference for CCR5 to a preference for CXCR4 in ∼50% of infected individuals. The change in coreceptor usage is the result of the complex interaction of the viral population with various cell populations of the immun...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 2005-06, Vol.13 (6), p.269-277
Hauptverfasser:	Regoes, Roland R., Bonhoeffer, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease Progression Evolution, Molecular HIV - immunology HIV - physiology HIV Infections - immunology HIV Infections - virology Humans Receptors, CCR5 - physiology Receptors, CXCR4 - physiology Selection, Genetic
Online-Zugang:	Volltext
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