LW protein: a promiscuous integrin receptor activated by adrenergic signaling

The LW blood group antigen glycoprotein, although part of the Rh macromolecular complex, is nonetheless a member of the intercellular adhesion molecule (ICAM) family. Thus, while it is only rarely clinically important in the setting of transfusion and pregnancy, LW is likely to contribute to red cel...

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Veröffentlicht in:	Transfusion clinique et biologique (Paris) 2006-03, Vol.13 (1), p.44-49
Hauptverfasser:	Delahunty, M., Zennadi, R., Telen, M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhérence cellulaire Adrenergic signaling Alleles Anemia, Sickle Cell - physiopathology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood and lymphatic vessels Blood group Blood Group Antigens - genetics Blood Platelets - metabolism Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Blood. Blood coagulation. Reticuloendothelial system Cardiology. Vascular system Cell adhesion Cell Adhesion - physiology Cell Adhesion Molecules - drug effects Cell Adhesion Molecules - genetics Cell Adhesion Molecules - physiology Chromosomes, Human, Pair 9 - genetics Cyclic AMP - physiology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Drépanocytose Endothelium, Vascular - pathology Epinephrine - pharmacology Erythrocytes - metabolism Erythrocytes - physiology Groupes sanguins Humans ICAM-4 Integrin alphaV - metabolism Integrin receptor Lymphocyte Function-Associated Antigen-1 - metabolism Medical sciences Pharmacology. Drug treatments Phosphorylation - drug effects Platelet Glycoprotein GPIIb-IIIa Complex - metabolism Polymorphism, Single Nucleotide Protein Processing, Post-Translational - drug effects Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - physiology Rh-Hr Blood-Group System - physiology Récepteur d'intégrines Sickle cell disease Signal Transduction - drug effects Signalisation adrénergique Thrombosis - physiopathology Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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