Central venous-arterial carbon dioxide difference as an indicator of cardiac index
The mixed venous-arterial (v-a) pCO(2) difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO(2), which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial p...
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| Veröffentlicht in: | Intensive care medicine 2005-06, Vol.31 (6), p.818-822 |
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| creator | CUSCHIERI, Joseph RIVERS, Emanuel P DONNINO, Michael W KATILIUS, Marius JACOBSEN, Gordon NGUYEN, H. Bryant PAMUKOV, Nikolai HORST, H. Mathilda |
| description | The mixed venous-arterial (v-a) pCO(2) difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO(2), which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial pCO(2) difference and CI.
Prospective, cohort study.
Intensive care unit of an urban tertiary care hospital.
Eighty-three consecutive intensive care unit patients.
Simultaneous blood gases from the arterial, pulmonary artery (PA), and central venous (CV) catheters were obtained. At the same time point, cardiac indices were measured by the thermodilution technique (an average of three measurements). The cardiac indices obtained by the venous-arterial differences were compared with those determined by thermodilution.
The correlation (R(2)) between the mixed venous-arterial pCO(2) difference and cardiac index was 0.903 (p |
| doi_str_mv | 10.1007/s00134-005-2602-8 |
| format | Article |
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Prospective, cohort study.
Intensive care unit of an urban tertiary care hospital.
Eighty-three consecutive intensive care unit patients.
Simultaneous blood gases from the arterial, pulmonary artery (PA), and central venous (CV) catheters were obtained. At the same time point, cardiac indices were measured by the thermodilution technique (an average of three measurements). The cardiac indices obtained by the venous-arterial differences were compared with those determined by thermodilution.
The correlation (R(2)) between the mixed venous-arterial pCO(2) difference and cardiac index was 0.903 (p <0.0001), and the correlation between the central venous-arterial pCO(2) difference and cardiac index was 0.892 (p <0.0001). The regression equations for these relationships were natural log (CI)=1.837-0.159 (v-a) CO(2) for the PA and natural log (CI)=1.787-0.151 (v-a) CO(2) for the CV (p <0.0001 for both). The root-mean-squared error for the PA and CV regression equations were 0.095 and 0.101, respectively.
Venous-arterial pCO(2) differences obtained from both the PA and CV circulations inversely correlate with the cardiac index. Substitution of a central for a mixed venous-arterial pCO(2) difference provides an accurate alternative method for calculation of cardiac output.</description><identifier>ISSN: 0342-4642</identifier><identifier>EISSN: 1432-1238</identifier><identifier>DOI: 10.1007/s00134-005-2602-8</identifier><identifier>PMID: 15803301</identifier><identifier>CODEN: ICMED9</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Gas Analysis - methods ; Carbon Dioxide - blood ; Cardiac Output ; Cardiology. Vascular system ; Catheterization, Central Venous ; Catheterization, Swan-Ganz ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care ; Female ; Hemodynamics ; Humans ; Intensive care medicine ; Linear Models ; Male ; Medical sciences ; Middle Aged ; Partial Pressure ; Prospective Studies</subject><ispartof>Intensive care medicine, 2005-06, Vol.31 (6), p.818-822</ispartof><rights>2005 INIST-CNRS</rights><rights>Springer-Verlag 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-f48c536fca8d6aa143ed5f72c76e0cbef1d54c09978c9852ba9a43cfb2b783973</citedby><cites>FETCH-LOGICAL-c356t-f48c536fca8d6aa143ed5f72c76e0cbef1d54c09978c9852ba9a43cfb2b783973</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16824592$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15803301$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CUSCHIERI, Joseph</creatorcontrib><creatorcontrib>RIVERS, Emanuel P</creatorcontrib><creatorcontrib>DONNINO, Michael W</creatorcontrib><creatorcontrib>KATILIUS, Marius</creatorcontrib><creatorcontrib>JACOBSEN, Gordon</creatorcontrib><creatorcontrib>NGUYEN, H. Bryant</creatorcontrib><creatorcontrib>PAMUKOV, Nikolai</creatorcontrib><creatorcontrib>HORST, H. Mathilda</creatorcontrib><title>Central venous-arterial carbon dioxide difference as an indicator of cardiac index</title><title>Intensive care medicine</title><addtitle>Intensive Care Med</addtitle><description>The mixed venous-arterial (v-a) pCO(2) difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO(2), which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial pCO(2) difference and CI.
Prospective, cohort study.
Intensive care unit of an urban tertiary care hospital.
Eighty-three consecutive intensive care unit patients.
Simultaneous blood gases from the arterial, pulmonary artery (PA), and central venous (CV) catheters were obtained. At the same time point, cardiac indices were measured by the thermodilution technique (an average of three measurements). The cardiac indices obtained by the venous-arterial differences were compared with those determined by thermodilution.
The correlation (R(2)) between the mixed venous-arterial pCO(2) difference and cardiac index was 0.903 (p <0.0001), and the correlation between the central venous-arterial pCO(2) difference and cardiac index was 0.892 (p <0.0001). The regression equations for these relationships were natural log (CI)=1.837-0.159 (v-a) CO(2) for the PA and natural log (CI)=1.787-0.151 (v-a) CO(2) for the CV (p <0.0001 for both). The root-mean-squared error for the PA and CV regression equations were 0.095 and 0.101, respectively.
Venous-arterial pCO(2) differences obtained from both the PA and CV circulations inversely correlate with the cardiac index. Substitution of a central for a mixed venous-arterial pCO(2) difference provides an accurate alternative method for calculation of cardiac output.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Gas Analysis - methods</subject><subject>Carbon Dioxide - blood</subject><subject>Cardiac Output</subject><subject>Cardiology. Vascular system</subject><subject>Catheterization, Central Venous</subject><subject>Catheterization, Swan-Ganz</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care</subject><subject>Female</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Linear Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Partial Pressure</subject><subject>Prospective Studies</subject><issn>0342-4642</issn><issn>1432-1238</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkE1rHDEMhk1paLZpf0AvZSi0Nzf-tudYluYDAoWQnI3GI4PDrCexZ0Py7-NhFwI9CYlHL9JDyDfOfnPG7HlljEtFGdNUGCao-0A2XElBuZDuI9kwqQRVRolT8rnWh0Zbo_kncsq1Y1IyviG3W8xLgal7xjzvK4WyYEmtD1CGOXdjml_SiK3GiAVzwA5qB7lLeUwBlrl0c1zhMUFYh_jyhZxEmCp-PdYzcn_x9257RW_-XV5v_9zQILVZaFQuaGliADcagHY3jjpaEaxBFgaMfNQqsL63LvROiwF6UDLEQQzWyd7KM_LrkPtY5qc91sXvUg04TZCxveKNdb3RUjfwx3_gw7wvud3mBTeCW6vXNH6AQplrLRj9Y0k7KK-eM7_a9gfbvtn2q23v2s73Y_B-2OH4vnHU24CfRwBqgCkWyCHVd844oXQv5BvhfYcj</recordid><startdate>20050601</startdate><enddate>20050601</enddate><creator>CUSCHIERI, Joseph</creator><creator>RIVERS, Emanuel P</creator><creator>DONNINO, Michael W</creator><creator>KATILIUS, Marius</creator><creator>JACOBSEN, Gordon</creator><creator>NGUYEN, H. 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Coronary intensive care</topic><topic>Female</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Linear Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Partial Pressure</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CUSCHIERI, Joseph</creatorcontrib><creatorcontrib>RIVERS, Emanuel P</creatorcontrib><creatorcontrib>DONNINO, Michael W</creatorcontrib><creatorcontrib>KATILIUS, Marius</creatorcontrib><creatorcontrib>JACOBSEN, Gordon</creatorcontrib><creatorcontrib>NGUYEN, H. Bryant</creatorcontrib><creatorcontrib>PAMUKOV, Nikolai</creatorcontrib><creatorcontrib>HORST, H. 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Bryant</au><au>PAMUKOV, Nikolai</au><au>HORST, H. Mathilda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central venous-arterial carbon dioxide difference as an indicator of cardiac index</atitle><jtitle>Intensive care medicine</jtitle><addtitle>Intensive Care Med</addtitle><date>2005-06-01</date><risdate>2005</risdate><volume>31</volume><issue>6</issue><spage>818</spage><epage>822</epage><pages>818-822</pages><issn>0342-4642</issn><eissn>1432-1238</eissn><coden>ICMED9</coden><abstract>The mixed venous-arterial (v-a) pCO(2) difference has been shown to be inversely correlated with the cardiac index (CI). A central venous pCO(2), which is easier to obtain, may provide similar information. The purpose of this study was to examine the correlation between the central venous-arterial pCO(2) difference and CI.
Prospective, cohort study.
Intensive care unit of an urban tertiary care hospital.
Eighty-three consecutive intensive care unit patients.
Simultaneous blood gases from the arterial, pulmonary artery (PA), and central venous (CV) catheters were obtained. At the same time point, cardiac indices were measured by the thermodilution technique (an average of three measurements). The cardiac indices obtained by the venous-arterial differences were compared with those determined by thermodilution.
The correlation (R(2)) between the mixed venous-arterial pCO(2) difference and cardiac index was 0.903 (p <0.0001), and the correlation between the central venous-arterial pCO(2) difference and cardiac index was 0.892 (p <0.0001). The regression equations for these relationships were natural log (CI)=1.837-0.159 (v-a) CO(2) for the PA and natural log (CI)=1.787-0.151 (v-a) CO(2) for the CV (p <0.0001 for both). The root-mean-squared error for the PA and CV regression equations were 0.095 and 0.101, respectively.
Venous-arterial pCO(2) differences obtained from both the PA and CV circulations inversely correlate with the cardiac index. Substitution of a central for a mixed venous-arterial pCO(2) difference provides an accurate alternative method for calculation of cardiac output.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>15803301</pmid><doi>10.1007/s00134-005-2602-8</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood and lymphatic vessels Blood Gas Analysis - methods Carbon Dioxide - blood Cardiac Output Cardiology. Vascular system Catheterization, Central Venous Catheterization, Swan-Ganz Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Hemodynamics Humans Intensive care medicine Linear Models Male Medical sciences Middle Aged Partial Pressure Prospective Studies |
| title | Central venous-arterial carbon dioxide difference as an indicator of cardiac index |
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