Mechanics of neutrophil phagocytosis: experiments and quantitative models

To quantitatively characterize the mechanical processes that drive phagocytosis, we observed the Fc[gamma]R-driven engulfment of antibody-coated beads of diameters 3 [micro]m to 11 [micro]m by initially spherical neutrophils. In particular, the time course of cell morphology, of bead motion and of c...

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Veröffentlicht in:	Journal of cell science 2006-05, Vol.119 (9), p.1903-1913
Hauptverfasser:	Herant, Marc, Heinrich, Volkmar, Dembo, Micah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - metabolism Cell Membrane - metabolism Cell Shape Cytoskeleton - metabolism Humans Mathematics Models, Theoretical Neutrophils - cytology Neutrophils - physiology Particle Size Phagocytosis - physiology Receptors, IgG - metabolism Stress, Mechanical Surface Properties
Online-Zugang:	Volltext
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