Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy
Objective: To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy. Design: Single case study. Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech, were performed before and after a trial of intrathecal baclofen in an adu...
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| Veröffentlicht in: | Clinical rehabilitation 2006-03, Vol.20 (3), p.228-231 |
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| creator | Leary, S M Gilpin, P Lockley, L Rodriguez, L Jarrett, L Stevenson, V L |
| description | Objective: To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy.
Design: Single case study.
Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech, were performed before and after a trial of intrathecal baclofen in an adult patient with spastic dysarthria due to cerebral palsy. The patient proceeded to intrathecal baclofen pump implantation and was reassessed after six months of continuous intrathecal baclofen therapy.
Results: Improvement in function including speech intelligibility was seen following the intrathecal baclofen trial. The improvement was sustained at six months post pump implantation.
Conclusions: Intrathecal baclofen improved functional intelligibility of speech in a carefully selected subject. The Assessment of Intelligibility of Dysarthric Speech was found to be a useful quantitative tool to assess the effect of intrathecal baclofen on spastic dysarthria. |
| doi_str_mv | 10.1191/0269215506cr940oa |
| format | Article |
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Design: Single case study.
Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech, were performed before and after a trial of intrathecal baclofen in an adult patient with spastic dysarthria due to cerebral palsy. The patient proceeded to intrathecal baclofen pump implantation and was reassessed after six months of continuous intrathecal baclofen therapy.
Results: Improvement in function including speech intelligibility was seen following the intrathecal baclofen trial. The improvement was sustained at six months post pump implantation.
Conclusions: Intrathecal baclofen improved functional intelligibility of speech in a carefully selected subject. The Assessment of Intelligibility of Dysarthric Speech was found to be a useful quantitative tool to assess the effect of intrathecal baclofen on spastic dysarthria.</description><identifier>ISSN: 0269-2155</identifier><identifier>EISSN: 1477-0873</identifier><identifier>DOI: 10.1191/0269215506cr940oa</identifier><identifier>PMID: 16634341</identifier><identifier>CODEN: CEHAEN</identifier><language>eng</language><publisher>Thousand Oaks, CA: Sage Publications</publisher><subject>Adult ; Baclofen - therapeutic use ; Cerebral palsy ; Cerebral Palsy - complications ; Cerebral Palsy - rehabilitation ; Drugs ; Dysarthria ; Dysarthria - etiology ; Dysarthria - rehabilitation ; GABA Agonists - therapeutic use ; Humans ; Infusion Pumps, Implantable ; Injections, Spinal ; Male ; Treatment methods</subject><ispartof>Clinical rehabilitation, 2006-03, Vol.20 (3), p.228-231</ispartof><rights>2006 Arnold</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-28686e61da0ccbf342c261f17e30f6510e392204fb75407c5cd6e0fb9a421a6a3</citedby><cites>FETCH-LOGICAL-c462t-28686e61da0ccbf342c261f17e30f6510e392204fb75407c5cd6e0fb9a421a6a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1191/0269215506cr940oa$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1191/0269215506cr940oa$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,12844,21817,27922,27923,30997,30998,43619,43620</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16634341$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leary, S M</creatorcontrib><creatorcontrib>Gilpin, P</creatorcontrib><creatorcontrib>Lockley, L</creatorcontrib><creatorcontrib>Rodriguez, L</creatorcontrib><creatorcontrib>Jarrett, L</creatorcontrib><creatorcontrib>Stevenson, V L</creatorcontrib><title>Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy</title><title>Clinical rehabilitation</title><addtitle>Clin Rehabil</addtitle><description>Objective: To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy.
Design: Single case study.
Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech, were performed before and after a trial of intrathecal baclofen in an adult patient with spastic dysarthria due to cerebral palsy. The patient proceeded to intrathecal baclofen pump implantation and was reassessed after six months of continuous intrathecal baclofen therapy.
Results: Improvement in function including speech intelligibility was seen following the intrathecal baclofen trial. The improvement was sustained at six months post pump implantation.
Conclusions: Intrathecal baclofen improved functional intelligibility of speech in a carefully selected subject. The Assessment of Intelligibility of Dysarthric Speech was found to be a useful quantitative tool to assess the effect of intrathecal baclofen on spastic dysarthria.</description><subject>Adult</subject><subject>Baclofen - therapeutic use</subject><subject>Cerebral palsy</subject><subject>Cerebral Palsy - complications</subject><subject>Cerebral Palsy - rehabilitation</subject><subject>Drugs</subject><subject>Dysarthria</subject><subject>Dysarthria - etiology</subject><subject>Dysarthria - rehabilitation</subject><subject>GABA Agonists - therapeutic use</subject><subject>Humans</subject><subject>Infusion Pumps, Implantable</subject><subject>Injections, Spinal</subject><subject>Male</subject><subject>Treatment methods</subject><issn>0269-2155</issn><issn>1477-0873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkU1LxDAQhoMouq7-AC9SPHjrOpOmSXsU8QsEL3oTSpqdaKTb1qQV-u_NsguCIp6GYZ555-Nl7ARhgVjiBXBZcsxzkMaXAjq9w2YolEqhUNkum63r6Ro4YIchvANAwQXuswOUMhOZwBl7uW8Hr4c3MrpJam2azlKbxNzrfkrcqvfdJ4XEjq0ZXNdGyLUDNY17dbVr3DAlnU1CT2TeYiUx5Kn2kep1E6YjtmdjpONtnLPnm-unq7v04fH2_uryITVC8iHlhSwkSVxqMKa2meCGS7SoKAMrcwTKSs5B2FrlApTJzVIS2LrUgqOWOpuz841u3PZjpDBUKxdM3FK31I2hkqooJSj1L5grFJBLjODZD_C9G308P1QcQPH47TJCuIGM70LwZKveu5X2U4VQrQ2qfhkUe063wmO9ouV3x9aRCCw2QNCv9D31b8Uvi2CalQ</recordid><startdate>200603</startdate><enddate>200603</enddate><creator>Leary, S M</creator><creator>Gilpin, P</creator><creator>Lockley, L</creator><creator>Rodriguez, L</creator><creator>Jarrett, L</creator><creator>Stevenson, V L</creator><general>Sage Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>200603</creationdate><title>Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy</title><author>Leary, S M ; Gilpin, P ; Lockley, L ; Rodriguez, L ; Jarrett, L ; Stevenson, V L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-28686e61da0ccbf342c261f17e30f6510e392204fb75407c5cd6e0fb9a421a6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Baclofen - therapeutic use</topic><topic>Cerebral palsy</topic><topic>Cerebral Palsy - complications</topic><topic>Cerebral Palsy - rehabilitation</topic><topic>Drugs</topic><topic>Dysarthria</topic><topic>Dysarthria - etiology</topic><topic>Dysarthria - rehabilitation</topic><topic>GABA Agonists - therapeutic use</topic><topic>Humans</topic><topic>Infusion Pumps, Implantable</topic><topic>Injections, Spinal</topic><topic>Male</topic><topic>Treatment methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leary, S M</creatorcontrib><creatorcontrib>Gilpin, P</creatorcontrib><creatorcontrib>Lockley, L</creatorcontrib><creatorcontrib>Rodriguez, L</creatorcontrib><creatorcontrib>Jarrett, L</creatorcontrib><creatorcontrib>Stevenson, V L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leary, S M</au><au>Gilpin, P</au><au>Lockley, L</au><au>Rodriguez, L</au><au>Jarrett, L</au><au>Stevenson, V L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy</atitle><jtitle>Clinical rehabilitation</jtitle><addtitle>Clin Rehabil</addtitle><date>2006-03</date><risdate>2006</risdate><volume>20</volume><issue>3</issue><spage>228</spage><epage>231</epage><pages>228-231</pages><issn>0269-2155</issn><eissn>1477-0873</eissn><coden>CEHAEN</coden><abstract>Objective: To assess the effect of intrathecal baclofen on spastic dysarthia in cerebral palsy.
Design: Single case study.
Methods: Functional outcome measures, including the Assessment of Intelligibility of Dysarthric Speech, were performed before and after a trial of intrathecal baclofen in an adult patient with spastic dysarthria due to cerebral palsy. The patient proceeded to intrathecal baclofen pump implantation and was reassessed after six months of continuous intrathecal baclofen therapy.
Results: Improvement in function including speech intelligibility was seen following the intrathecal baclofen trial. The improvement was sustained at six months post pump implantation.
Conclusions: Intrathecal baclofen improved functional intelligibility of speech in a carefully selected subject. The Assessment of Intelligibility of Dysarthric Speech was found to be a useful quantitative tool to assess the effect of intrathecal baclofen on spastic dysarthria.</abstract><cop>Thousand Oaks, CA</cop><pub>Sage Publications</pub><pmid>16634341</pmid><doi>10.1191/0269215506cr940oa</doi><tpages>4</tpages></addata></record> |
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| ispartof | Clinical rehabilitation, 2006-03, Vol.20 (3), p.228-231 |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); SAGE Complete A-Z List |
| subjects | Adult Baclofen - therapeutic use Cerebral palsy Cerebral Palsy - complications Cerebral Palsy - rehabilitation Drugs Dysarthria Dysarthria - etiology Dysarthria - rehabilitation GABA Agonists - therapeutic use Humans Infusion Pumps, Implantable Injections, Spinal Male Treatment methods |
| title | Intrathecal baclofen therapy improves functional intelligibility of speech in cerebral palsy |
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