Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial
The reported relationships between nerve conduction studies (NCS) and outcome measures in carpal tunnel syndrome (CTS) are weak to moderate. However, selection of patients may have confounded nonrandomized studies. NCS have potentially great value in selecting patients for a specific treatment and i...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical neurophysiology 2005-06, Vol.22 (3), p.216-221 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 221 |
|---|---|
| container_issue | 3 |
| container_start_page | 216 |
| container_title | Journal of clinical neurophysiology |
| container_volume | 22 |
| creator | Schrijver, Hans M Gerritsen, Annette A.M Strijers, Rob L.M Uitdehaag, Bernard M.J Scholten, Rob J.P. M de Vet, Henrica C.W Bouter, Lex M |
| description | The reported relationships between nerve conduction studies (NCS) and outcome measures in carpal tunnel syndrome (CTS) are weak to moderate. However, selection of patients may have confounded nonrandomized studies. NCS have potentially great value in selecting patients for a specific treatment and in objectively assessing the efficacy of treatments in CTS, especially if they correlate significantly with clinical outcome measures. To investigate the relationship between clinical outcome measures for the severity of complaints and NCS in patients treated for CTS, data were obtained from a multicenter randomized controlled trial on the efficacy of splinting versus surgery for CTS. At baseline and 12 months after randomization, clinical outcome measures were assessed and NCS were performed. In total, 138 patients completed the questionnaires and underwent repeated NCS. Relationships were analyzed with Spearman rank correlation coefficients and Pearson correlation coefficients. All NCS parameters showed highly significant improvement compared with baseline (P < 0.001). Modest correlations ( |
| doi_str_mv | 10.1097/01.WNP.0000167936.75404.C3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_67895443</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>20487492</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2859-37b851cec0d0b2cce6541cedd8ed3b07bbcdb5d3042c636a298b5e79edb807dd3</originalsourceid><addsrcrecordid>eNqFkctu1TAQhi0EoofCKyCLBbsEx9eYHYooIB3aqj2IZeTLQAOOfWonrcoT8Nj4qO2a2cz8M5_-kWYQetORtiNavSNd-_30vCU1Oqk0k60SnPB2YE_QphNMNZ0k7CnaEMVkQ6joj9CLUn5VXDFGn6OjTmjGuBYb9HdIOUMwyxR_4lPIN4CHFP3qlilFfLmsfoKCTfR4CFOcnAn4bF1cmgF_BVPWXKcVHEze19FujRECvryLPlfkPd5CKSkWfFIlNviiGqV5-gP-sGXJKYRa7vJkwkv07IcJBV495GP07eTjbvjcbM8-fRk-bJs97YVumLK96Bw44omlzoEUvErve_DMEmWt81Z4Rjh1kklDdW8FKA3e9kR5z47R23vffU7XK5RlnKfiIAQTIa1llKrXgnP2X5AS3iuuaQVfP4CrncGP-zzNJt-Nj0euAL8HblNYIJffYb2FPF6BCcvVeHgjl7prKCGCyKqaQ0uzf2uwkvw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20487492</pqid></control><display><type>article</type><title>Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Schrijver, Hans M ; Gerritsen, Annette A.M ; Strijers, Rob L.M ; Uitdehaag, Bernard M.J ; Scholten, Rob J.P. M ; de Vet, Henrica C.W ; Bouter, Lex M</creator><creatorcontrib>Schrijver, Hans M ; Gerritsen, Annette A.M ; Strijers, Rob L.M ; Uitdehaag, Bernard M.J ; Scholten, Rob J.P. M ; de Vet, Henrica C.W ; Bouter, Lex M</creatorcontrib><description>The reported relationships between nerve conduction studies (NCS) and outcome measures in carpal tunnel syndrome (CTS) are weak to moderate. However, selection of patients may have confounded nonrandomized studies. NCS have potentially great value in selecting patients for a specific treatment and in objectively assessing the efficacy of treatments in CTS, especially if they correlate significantly with clinical outcome measures. To investigate the relationship between clinical outcome measures for the severity of complaints and NCS in patients treated for CTS, data were obtained from a multicenter randomized controlled trial on the efficacy of splinting versus surgery for CTS. At baseline and 12 months after randomization, clinical outcome measures were assessed and NCS were performed. In total, 138 patients completed the questionnaires and underwent repeated NCS. Relationships were analyzed with Spearman rank correlation coefficients and Pearson correlation coefficients. All NCS parameters showed highly significant improvement compared with baseline (P < 0.001). Modest correlations (<0.4) were found between the neurophysiologic and clinical outcome measures after 12 months, and between the changes in these different categories of outcome measures. This study confirms that the parameters of NCS improve significantly after treatment for CTS, but the modest correlations between neurophysiologic and clinical outcome measures do not support that NCS are routinely performed in clinical practice to evaluate treatment effects. However, studies investigating the effects of treatment for CTS should incorporate both clinical outcome measures and NCS, because they are complementary. Furthermore, NCS can provide additional information to the clinician when treatment effects are unsatisfactory.</description><identifier>ISSN: 0736-0258</identifier><identifier>EISSN: 1537-1603</identifier><identifier>DOI: 10.1097/01.WNP.0000167936.75404.C3</identifier><identifier>PMID: 15933495</identifier><language>eng</language><publisher>United States: Copyright American Clinical Neurophysiology Society</publisher><subject>Adult ; Carpal Tunnel Syndrome - physiopathology ; Carpal Tunnel Syndrome - therapy ; Electric Stimulation - methods ; Electromyography ; Female ; Follow-Up Studies ; Humans ; Male ; Median Nerve - physiopathology ; Median Nerve - radiation effects ; Middle Aged ; Neural Conduction - physiology ; Neural Conduction - radiation effects ; Neurologic Examination ; Outcome Assessment (Health Care) ; Reaction Time - physiology ; Reaction Time - radiation effects ; Recovery of Function ; Sensitivity and Specificity ; Sensory Thresholds ; Severity of Illness Index ; Statistics as Topic ; Surveys and Questionnaires</subject><ispartof>Journal of clinical neurophysiology, 2005-06, Vol.22 (3), p.216-221</ispartof><rights>Copyright © 2005 American Clinical Neurophysiology Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27926,27927</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15933495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schrijver, Hans M</creatorcontrib><creatorcontrib>Gerritsen, Annette A.M</creatorcontrib><creatorcontrib>Strijers, Rob L.M</creatorcontrib><creatorcontrib>Uitdehaag, Bernard M.J</creatorcontrib><creatorcontrib>Scholten, Rob J.P. M</creatorcontrib><creatorcontrib>de Vet, Henrica C.W</creatorcontrib><creatorcontrib>Bouter, Lex M</creatorcontrib><title>Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial</title><title>Journal of clinical neurophysiology</title><addtitle>J Clin Neurophysiol</addtitle><description>The reported relationships between nerve conduction studies (NCS) and outcome measures in carpal tunnel syndrome (CTS) are weak to moderate. However, selection of patients may have confounded nonrandomized studies. NCS have potentially great value in selecting patients for a specific treatment and in objectively assessing the efficacy of treatments in CTS, especially if they correlate significantly with clinical outcome measures. To investigate the relationship between clinical outcome measures for the severity of complaints and NCS in patients treated for CTS, data were obtained from a multicenter randomized controlled trial on the efficacy of splinting versus surgery for CTS. At baseline and 12 months after randomization, clinical outcome measures were assessed and NCS were performed. In total, 138 patients completed the questionnaires and underwent repeated NCS. Relationships were analyzed with Spearman rank correlation coefficients and Pearson correlation coefficients. All NCS parameters showed highly significant improvement compared with baseline (P < 0.001). Modest correlations (<0.4) were found between the neurophysiologic and clinical outcome measures after 12 months, and between the changes in these different categories of outcome measures. This study confirms that the parameters of NCS improve significantly after treatment for CTS, but the modest correlations between neurophysiologic and clinical outcome measures do not support that NCS are routinely performed in clinical practice to evaluate treatment effects. However, studies investigating the effects of treatment for CTS should incorporate both clinical outcome measures and NCS, because they are complementary. Furthermore, NCS can provide additional information to the clinician when treatment effects are unsatisfactory.</description><subject>Adult</subject><subject>Carpal Tunnel Syndrome - physiopathology</subject><subject>Carpal Tunnel Syndrome - therapy</subject><subject>Electric Stimulation - methods</subject><subject>Electromyography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Median Nerve - physiopathology</subject><subject>Median Nerve - radiation effects</subject><subject>Middle Aged</subject><subject>Neural Conduction - physiology</subject><subject>Neural Conduction - radiation effects</subject><subject>Neurologic Examination</subject><subject>Outcome Assessment (Health Care)</subject><subject>Reaction Time - physiology</subject><subject>Reaction Time - radiation effects</subject><subject>Recovery of Function</subject><subject>Sensitivity and Specificity</subject><subject>Sensory Thresholds</subject><subject>Severity of Illness Index</subject><subject>Statistics as Topic</subject><subject>Surveys and Questionnaires</subject><issn>0736-0258</issn><issn>1537-1603</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1TAQhi0EoofCKyCLBbsEx9eYHYooIB3aqj2IZeTLQAOOfWonrcoT8Nj4qO2a2cz8M5_-kWYQetORtiNavSNd-_30vCU1Oqk0k60SnPB2YE_QphNMNZ0k7CnaEMVkQ6joj9CLUn5VXDFGn6OjTmjGuBYb9HdIOUMwyxR_4lPIN4CHFP3qlilFfLmsfoKCTfR4CFOcnAn4bF1cmgF_BVPWXKcVHEze19FujRECvryLPlfkPd5CKSkWfFIlNviiGqV5-gP-sGXJKYRa7vJkwkv07IcJBV495GP07eTjbvjcbM8-fRk-bJs97YVumLK96Bw44omlzoEUvErve_DMEmWt81Z4Rjh1kklDdW8FKA3e9kR5z47R23vffU7XK5RlnKfiIAQTIa1llKrXgnP2X5AS3iuuaQVfP4CrncGP-zzNJt-Nj0euAL8HblNYIJffYb2FPF6BCcvVeHgjl7prKCGCyKqaQ0uzf2uwkvw</recordid><startdate>200506</startdate><enddate>200506</enddate><creator>Schrijver, Hans M</creator><creator>Gerritsen, Annette A.M</creator><creator>Strijers, Rob L.M</creator><creator>Uitdehaag, Bernard M.J</creator><creator>Scholten, Rob J.P. M</creator><creator>de Vet, Henrica C.W</creator><creator>Bouter, Lex M</creator><general>Copyright American Clinical Neurophysiology Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200506</creationdate><title>Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial</title><author>Schrijver, Hans M ; Gerritsen, Annette A.M ; Strijers, Rob L.M ; Uitdehaag, Bernard M.J ; Scholten, Rob J.P. M ; de Vet, Henrica C.W ; Bouter, Lex M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2859-37b851cec0d0b2cce6541cedd8ed3b07bbcdb5d3042c636a298b5e79edb807dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Carpal Tunnel Syndrome - physiopathology</topic><topic>Carpal Tunnel Syndrome - therapy</topic><topic>Electric Stimulation - methods</topic><topic>Electromyography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Median Nerve - physiopathology</topic><topic>Median Nerve - radiation effects</topic><topic>Middle Aged</topic><topic>Neural Conduction - physiology</topic><topic>Neural Conduction - radiation effects</topic><topic>Neurologic Examination</topic><topic>Outcome Assessment (Health Care)</topic><topic>Reaction Time - physiology</topic><topic>Reaction Time - radiation effects</topic><topic>Recovery of Function</topic><topic>Sensitivity and Specificity</topic><topic>Sensory Thresholds</topic><topic>Severity of Illness Index</topic><topic>Statistics as Topic</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schrijver, Hans M</creatorcontrib><creatorcontrib>Gerritsen, Annette A.M</creatorcontrib><creatorcontrib>Strijers, Rob L.M</creatorcontrib><creatorcontrib>Uitdehaag, Bernard M.J</creatorcontrib><creatorcontrib>Scholten, Rob J.P. M</creatorcontrib><creatorcontrib>de Vet, Henrica C.W</creatorcontrib><creatorcontrib>Bouter, Lex M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical neurophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schrijver, Hans M</au><au>Gerritsen, Annette A.M</au><au>Strijers, Rob L.M</au><au>Uitdehaag, Bernard M.J</au><au>Scholten, Rob J.P. M</au><au>de Vet, Henrica C.W</au><au>Bouter, Lex M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial</atitle><jtitle>Journal of clinical neurophysiology</jtitle><addtitle>J Clin Neurophysiol</addtitle><date>2005-06</date><risdate>2005</risdate><volume>22</volume><issue>3</issue><spage>216</spage><epage>221</epage><pages>216-221</pages><issn>0736-0258</issn><eissn>1537-1603</eissn><abstract>The reported relationships between nerve conduction studies (NCS) and outcome measures in carpal tunnel syndrome (CTS) are weak to moderate. However, selection of patients may have confounded nonrandomized studies. NCS have potentially great value in selecting patients for a specific treatment and in objectively assessing the efficacy of treatments in CTS, especially if they correlate significantly with clinical outcome measures. To investigate the relationship between clinical outcome measures for the severity of complaints and NCS in patients treated for CTS, data were obtained from a multicenter randomized controlled trial on the efficacy of splinting versus surgery for CTS. At baseline and 12 months after randomization, clinical outcome measures were assessed and NCS were performed. In total, 138 patients completed the questionnaires and underwent repeated NCS. Relationships were analyzed with Spearman rank correlation coefficients and Pearson correlation coefficients. All NCS parameters showed highly significant improvement compared with baseline (P < 0.001). Modest correlations (<0.4) were found between the neurophysiologic and clinical outcome measures after 12 months, and between the changes in these different categories of outcome measures. This study confirms that the parameters of NCS improve significantly after treatment for CTS, but the modest correlations between neurophysiologic and clinical outcome measures do not support that NCS are routinely performed in clinical practice to evaluate treatment effects. However, studies investigating the effects of treatment for CTS should incorporate both clinical outcome measures and NCS, because they are complementary. Furthermore, NCS can provide additional information to the clinician when treatment effects are unsatisfactory.</abstract><cop>United States</cop><pub>Copyright American Clinical Neurophysiology Society</pub><pmid>15933495</pmid><doi>10.1097/01.WNP.0000167936.75404.C3</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0736-0258 |
| ispartof | Journal of clinical neurophysiology, 2005-06, Vol.22 (3), p.216-221 |
| issn | 0736-0258 1537-1603 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67895443 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Carpal Tunnel Syndrome - physiopathology Carpal Tunnel Syndrome - therapy Electric Stimulation - methods Electromyography Female Follow-Up Studies Humans Male Median Nerve - physiopathology Median Nerve - radiation effects Middle Aged Neural Conduction - physiology Neural Conduction - radiation effects Neurologic Examination Outcome Assessment (Health Care) Reaction Time - physiology Reaction Time - radiation effects Recovery of Function Sensitivity and Specificity Sensory Thresholds Severity of Illness Index Statistics as Topic Surveys and Questionnaires |
| title | Correlating Nerve Conduction Studies and Clinical Outcome Measures on Carpal Tunnel Syndrome: Lessons From a Randomized Controlled Trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T00%3A50%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Correlating%20Nerve%20Conduction%20Studies%20and%20Clinical%20Outcome%20Measures%20on%20Carpal%20Tunnel%20Syndrome:%20Lessons%20From%20a%20Randomized%20Controlled%20Trial&rft.jtitle=Journal%20of%20clinical%20neurophysiology&rft.au=Schrijver,%20Hans%20M&rft.date=2005-06&rft.volume=22&rft.issue=3&rft.spage=216&rft.epage=221&rft.pages=216-221&rft.issn=0736-0258&rft.eissn=1537-1603&rft_id=info:doi/10.1097/01.WNP.0000167936.75404.C3&rft_dat=%3Cproquest_pubme%3E20487492%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=20487492&rft_id=info:pmid/15933495&rfr_iscdi=true |