Pseudoexfoliation syndrome and asymptomatic myocardial dysfunction
The purpose of this study was to investigate the frequency of asymptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrome. Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9+/-5.6 y...
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| Veröffentlicht in: | Graefe's archive for clinical and experimental ophthalmology 2005-05, Vol.243 (5), p.446-449 |
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| container_title | Graefe's archive for clinical and experimental ophthalmology |
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| creator | Bojić, Lovro Ermacora, Ratko Polić, Stojan Ivanisević, Milan Mandić, Zdravko Rogosić, Veljko Lesin, Mladen |
| description | The purpose of this study was to investigate the frequency of asymptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrome.
Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9+/-5.6 years, and 24 healthy volunteers aged 63.9+/-6.5 years. Left ventricular (LV) systolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early fast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velocity time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pressure at the end of filling (LVEDP) and a pulmonary capillary wedge pressure (PCWP).
Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseudoexfoliation syndrome and controls (P>0.05). A significant difference (P |
| doi_str_mv | 10.1007/s00417-004-1074-9 |
| format | Article |
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Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9+/-5.6 years, and 24 healthy volunteers aged 63.9+/-6.5 years. Left ventricular (LV) systolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early fast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velocity time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pressure at the end of filling (LVEDP) and a pulmonary capillary wedge pressure (PCWP).
Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseudoexfoliation syndrome and controls (P>0.05). A significant difference (P<0.05) was found with regard to the diastolic filling parameters: E (61.6+/-15.1 vs 83.7+/-21.4), ratio E/A (0.8+/-0.1 vs 1.1+/-0.2), VTIE (8.6+/-1.8 vs 9.8+/-1.9), VTIA (10.3+/-2.4 vs 7.8+/-1.6) and ratio VTIA/VTIE (1.2+/-0.2 vs 0.8+/-0.2).
Our study suggests the possibility of an association between patients with pseudoexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunction.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/s00417-004-1074-9</identifier><identifier>PMID: 15599584</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Aged ; Diastole ; Echocardiography ; Echocardiography, Doppler, Pulsed ; Exfoliation Syndrome - complications ; Exfoliation Syndrome - diagnosis ; Female ; Humans ; Male ; Middle Aged ; Ophthalmology ; Ventricular Dysfunction, Left - complications ; Ventricular Dysfunction, Left - diagnosis</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 2005-05, Vol.243 (5), p.446-449</ispartof><rights>Springer-Verlag 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15599584$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bojić, Lovro</creatorcontrib><creatorcontrib>Ermacora, Ratko</creatorcontrib><creatorcontrib>Polić, Stojan</creatorcontrib><creatorcontrib>Ivanisević, Milan</creatorcontrib><creatorcontrib>Mandić, Zdravko</creatorcontrib><creatorcontrib>Rogosić, Veljko</creatorcontrib><creatorcontrib>Lesin, Mladen</creatorcontrib><title>Pseudoexfoliation syndrome and asymptomatic myocardial dysfunction</title><title>Graefe's archive for clinical and experimental ophthalmology</title><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><description>The purpose of this study was to investigate the frequency of asymptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrome.
Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9+/-5.6 years, and 24 healthy volunteers aged 63.9+/-6.5 years. Left ventricular (LV) systolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early fast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velocity time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pressure at the end of filling (LVEDP) and a pulmonary capillary wedge pressure (PCWP).
Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseudoexfoliation syndrome and controls (P>0.05). A significant difference (P<0.05) was found with regard to the diastolic filling parameters: E (61.6+/-15.1 vs 83.7+/-21.4), ratio E/A (0.8+/-0.1 vs 1.1+/-0.2), VTIE (8.6+/-1.8 vs 9.8+/-1.9), VTIA (10.3+/-2.4 vs 7.8+/-1.6) and ratio VTIA/VTIE (1.2+/-0.2 vs 0.8+/-0.2).
Our study suggests the possibility of an association between patients with pseudoexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunction.</description><subject>Aged</subject><subject>Diastole</subject><subject>Echocardiography</subject><subject>Echocardiography, Doppler, Pulsed</subject><subject>Exfoliation Syndrome - complications</subject><subject>Exfoliation Syndrome - diagnosis</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Ventricular Dysfunction, Left - complications</subject><subject>Ventricular Dysfunction, Left - diagnosis</subject><issn>0721-832X</issn><issn>1435-702X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpd0EtLxDAQAOAgiruu_gAvUjx4i-b9OOriCxb0oLC3kjYpdGmamrRg__1GXC9eZhjmm2EYAC4xusUIybuEEMMS5ggxkgzqI7DEjHIoEdkegyWSBENFyXYBzlLaoQwpx6dggTnXmiu2BA_vyU02uO8mdK0Z29AXae5tDN4VpreFSbMfxuBzqy78HGoTbWu6ws6pmfr6Z-AcnDSmS-7ikFfg8-nxY_0CN2_Pr-v7DRywECMUXCpltHGNU5IJyTjJlbZVpSlholLWcKE0d9ZpS6vsDJacUVsjxW3N6Qrc_O4dYviaXBpL36badZ3pXZhSKaTSlCGU4fU_uAtT7PNtJaFIKqKJyujqgKbKO1sOsfUmzuXfa-geiYhnKw</recordid><startdate>200505</startdate><enddate>200505</enddate><creator>Bojić, Lovro</creator><creator>Ermacora, Ratko</creator><creator>Polić, Stojan</creator><creator>Ivanisević, Milan</creator><creator>Mandić, Zdravko</creator><creator>Rogosić, Veljko</creator><creator>Lesin, Mladen</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>200505</creationdate><title>Pseudoexfoliation syndrome and asymptomatic myocardial dysfunction</title><author>Bojić, Lovro ; 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Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9+/-5.6 years, and 24 healthy volunteers aged 63.9+/-6.5 years. Left ventricular (LV) systolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early fast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velocity time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pressure at the end of filling (LVEDP) and a pulmonary capillary wedge pressure (PCWP).
Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseudoexfoliation syndrome and controls (P>0.05). A significant difference (P<0.05) was found with regard to the diastolic filling parameters: E (61.6+/-15.1 vs 83.7+/-21.4), ratio E/A (0.8+/-0.1 vs 1.1+/-0.2), VTIE (8.6+/-1.8 vs 9.8+/-1.9), VTIA (10.3+/-2.4 vs 7.8+/-1.6) and ratio VTIA/VTIE (1.2+/-0.2 vs 0.8+/-0.2).
Our study suggests the possibility of an association between patients with pseudoexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunction.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>15599584</pmid><doi>10.1007/s00417-004-1074-9</doi><tpages>4</tpages></addata></record> |
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| subjects | Aged Diastole Echocardiography Echocardiography, Doppler, Pulsed Exfoliation Syndrome - complications Exfoliation Syndrome - diagnosis Female Humans Male Middle Aged Ophthalmology Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - diagnosis |
| title | Pseudoexfoliation syndrome and asymptomatic myocardial dysfunction |
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