Wnt signalling and prostate cancer

The Wnt signalling pathway plays a role in the direction of embryological development and maintenance of stem cell populations. Heritable alterations in genes encoding molecules of the Wnt pathway, including mutation and epigenetic events, have been demonstrated in a variety of cancers. It has been...

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Veröffentlicht in:	Prostate cancer and prostatic diseases 2005-06, Vol.8 (2), p.119-126
Hauptverfasser:	Yardy, G W, Brewster, S F
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptors beta Catenin Biomedical and Life Sciences Biomedicine Cancer Research Cell Transformation, Neoplastic Cytoskeletal Proteins - physiology Epigenetics Gene expression Genes Humans Intercellular Signaling Peptides and Proteins - biosynthesis Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - physiology Male Malignancy Mutation Prognosis Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - physiopathology Prostatic Neoplasms - therapy Protein-Tyrosine Kinases Receptors, Androgen - physiology review Signal Transduction Signaling Stem cells Trans-Activators - physiology Tumors Wnt protein Wnt Proteins β-Catenin
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