A fibronectin fragment alters the metabolism by rabbit intervertebral disc cells in vitro

A biochemical and gene expression study was conducted to determine the effects of the 30-kDa N-terminal fibronectin fragment (Fn-f) on the glycosaminoglycan content of nucleus pulposus (NP) explant cultures, and on the gene expression profile of NP cells in alginate culture. To determine the effects...

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Veröffentlicht in:	Spine (Philadelphia, Pa. 1976) Pa. 1976), 2005-06, Vol.30 (11), p.1242-1246
Hauptverfasser:	ANDERSON, D. Greg, XUDONG LI, BALIAN, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Cerebrospinal fluid. Meninges. Spinal cord Collagenases - genetics Collagenases - metabolism Development. Senescence. Regeneration. Transplantation Dose-Response Relationship, Drug Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism fas Receptor - genetics fas Receptor - metabolism Fibronectins - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Intervertebral Disc - drug effects Intervertebral Disc - metabolism Intervertebral Disc - pathology Isolated neuron and nerve. Neuroglia Matrix Metalloproteinase 13 Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Medical sciences Nervous system (semeiology, syndromes) Neurology Peptide Fragments - pharmacology Rabbits RNA, Messenger - metabolism Vertebrates: nervous system and sense organs
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