From stem cells to viable autologous semilunar heart valve

An estimated 275,000 patients undergo heart valve replacement each year. However, existing solutions for valve replacement are complicated by the morbidity associated with lifelong anticoagulation of mechanical valves and the limited durability of bioprostheses. Recent advances in tissue engineering...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2005-05, Vol.111 (21), p.2783-2791
Hauptverfasser:	SUTHERLAND, Fraser W. H, PERRY, Tjorvi E, SCHOEN, Frederick J, MAYER, John E, YING YU, SHERWOOD, Megan C, RABKIN, Elena, MASUDA, Yutaka, GARCIA, G. Alejandra, MCLELLAN, Dawn L, ENGELMAYR, George C, SACKS, Michael S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials Biological and medical sciences Bioprosthesis Blood and lymphatic vessels Blood vessels and receptors Cardiology. Vascular system Cell Differentiation Cell Lineage Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Echocardiography Fundamental and applied biological sciences. Psychology Heart Valve Prosthesis Heart Valve Prosthesis Implantation Immunophenotyping Medical sciences Mesenchymal Stromal Cells - cytology Pluripotent Stem Cells Pulmonary Valve Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Sheep Tissue Engineering - methods Transplantation, Autologous Vertebrates: cardiovascular system
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