Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy

To identify molecules to serve as diagnostic markers for renal cell carcinoma (RCC) and as targets for novel therapeutic drugs, we investigated genome-wide expression profiles of RCCs using a cDNA microarray. We subsequently confirmed that hypoxia-inducible protein-2 (HIG2) was expressed exclusively...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2005-06, Vol.65 (11), p.4817-4826
Hauptverfasser:	TOGASHI, Akira, KATAGIRI, Toyomasa, NAKAMURA, Yusuke, ASHIDA, Shingo, FUJIOKA, Tomoaki, MARUYAMA, Osamu, WAKUMOTO, Yoshiaki, SAKAMOTO, Yoshiro, FUJIME, Makoto, KAWACHI, Yoshio, SHUIN, Taro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Carcinoma, Renal Cell - therapy Cell Growth Processes - physiology Cercopithecus aethiops COS Cells HCT116 Cells HeLa Cells Humans Kidney Neoplasms - genetics Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Kidney Neoplasms - therapy Kidneys Medical sciences Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neoplasm Proteins - physiology Nephrology. Urinary tract diseases Oligonucleotide Array Sequence Analysis Pharmacology. Drug treatments Transfection Tumors Tumors of the urinary system Up-Regulation
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