The GC-MS detection and characterization of neopine resulting from opium use and codeine metabolism and its potential as an opiate-product-use marker

Neopine, a minor opium alkaloid and an isomer of codeine (also known as beta-codeine), has been detected in both the urine of opium users and pharmaceutical codeine users. The characterization of neopine was achieved by comparison of the mass spectra and GC retention times of the trimethylsilyl deri...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2005-06, Vol.382 (3), p.830-835
Hauptverfasser:	Al-Amri, Abdel M, Smith, Roger M, El-Haj, Babiker M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - chemistry Codeine - chemistry Codeine - metabolism Gas Chromatography-Mass Spectrometry - instrumentation Gas Chromatography-Mass Spectrometry - methods Humans Hydrocodone - analogs & derivatives Hydrocodone - analysis Hydrogen-Ion Concentration Molecular Structure Opium - chemistry Opium - urine
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