An Inducible Mouse Model for PAX2-Dependent Glomerular Disease: Insights into a Complex Pathogenesis

Pax2 is a transcription factor with important functions during kidney development [1–3]. Ectopic expression of Pax2 in podocytes has been reported in various glomerular diseases [4–7], but the functional relevance remains unknown. We developed an inducible mouse model that allows activation of Pax2...

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