LC/MS/MS measurement of gentamicin in bovine plasma, urine, milk, and biopsy samples taken from kidneys of standing animals

Methods for the measurement of gentamicin concentration in several bovine tissues were developed and validated. A novel liquid chromatographic (LC) technique employed trifluoroacetic acid in the mobile phase so that all gentamicin components co-eluted. Analytes were ionized by positive-ion pneumatic...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2005-07, Vol.821 (1), p.22-30
Hauptverfasser:	HELLER, David N, PEGGINS, James O, NOCHETTO, Cristina B, SMITH, Michelle L, CHIESA, O. Alberto, MOULTON, Keesla
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Biopsy - veterinary Cattle Chemical Fractionation - methods Chromatography, Liquid - methods Female Fundamental and applied biological sciences. Psychology General pharmacology Gentamicins - analysis Gentamicins - metabolism Kidney - chemistry Mass Spectrometry - methods Medical sciences Milk - chemistry Pharmacology. Drug treatments
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