Comparison of the antioxidant and vascular effects of gliclazide and glibenclamide in Type 2 diabetic patients: a randomized crossover study

The aim of the present study is to compare the short-term effects of gliclazide and glibenclamide on the oxidative state and vascular endothelium function of Type 2 diabetic patients in an observer-blinded, randomized crossover study. Thirteen Type 2 diabetic patients were enrolled: one group of sev...

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Veröffentlicht in:	Journal of diabetes and its complications 2006-05, Vol.20 (3), p.179-183
Hauptverfasser:	Shimabukuro, Michio, Higa, Namio, Takasu, Nobuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants Antioxidants - therapeutic use Blood Flow Velocity - drug effects Blood Pressure - drug effects Body Mass Index Cross-Over Studies Diabetes Mellitus, Type 2 - drug therapy Dinoprost - analogs & derivatives Dinoprost - urine Double-Blind Method Female Forearm - blood supply Free radicals Gliclazide - therapeutic use Glucose Glyburide - therapeutic use Glycated Hemoglobin A - analysis Humans Hyperemia - diagnosis Male Middle Aged Oxidative stress Regional Blood Flow - drug effects Rodents Vascular Resistance - drug effects
Online-Zugang:	Volltext
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