Metagenomic gene discovery: past, present and future
It is now widely accepted that the application of standard microbiological methods for the recovery of microorganisms from the environment has had limited success in providing access to the true extent of microbial biodiversity. It follows that much of the extant microbial genetic diversity (collect...
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| Veröffentlicht in: | Trends in biotechnology (Regular ed.) 2005-06, Vol.23 (6), p.321-329 |
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| container_end_page | 329 |
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| container_issue | 6 |
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| container_title | Trends in biotechnology (Regular ed.) |
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| creator | Cowan, Don Meyer, Quinton Stafford, William Muyanga, Samson Cameron, Rory Wittwer, Pia |
| description | It is now widely accepted that the application of standard microbiological methods for the recovery of microorganisms from the environment has had limited success in providing access to the true extent of microbial biodiversity. It follows that much of the extant microbial genetic diversity (collectively termed the metagenome) remains unexploited, an issue of considerable relevance to a wider understanding of microbial communities and of considerable importance to the biotechnology industry. The recent development of technologies designed to access this wealth of genetic information through environmental nucleic acid extraction has provided a means of avoiding the limitations of culture-dependent genetic exploitation. |
| doi_str_mv | 10.1016/j.tibtech.2005.04.001 |
| format | Article |
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| identifier | ISSN: 0167-7799 |
| ispartof | Trends in biotechnology (Regular ed.), 2005-06, Vol.23 (6), p.321-329 |
| issn | 0167-7799 1879-3096 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland |
| subjects | Bacteria - genetics Biodiversity Biological and medical sciences Biotechnology Cloning, Molecular - methods Environmental Microbiology Fundamental and applied biological sciences. Psychology Genetics, Microbial - methods Genetics, Microbial - trends Genome, Bacterial |
| title | Metagenomic gene discovery: past, present and future |
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