DAF-16/FOXO Regulates Transcription of cki-1/Cip/Kip and Repression of lin-4 during C. elegans L1 Arrest

Development is typically studied as a continuous process under laboratory conditions, but wild animals often develop in variable and stressful environments. C. elegans larvae hatch in a developmentally arrested state (L1 arrest) and initiate post-embryonic development only in the presence of food (...

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Veröffentlicht in:	Current biology 2006-04, Vol.16 (8), p.780-785
Hauptverfasser:	Baugh, L. Ryan, Sternberg, Paul W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - growth & development Caenorhabditis elegans Proteins - metabolism Caenorhabditis elegans Proteins - physiology Cyclin-Dependent Kinase Inhibitor Proteins - metabolism DEVBIO Forkhead Transcription Factors Gene Expression Regulation, Developmental MicroRNAs Nutritional Requirements Repressor Proteins - metabolism SIGNALING Somatomedins - physiology Transcription Factors - physiology
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