A mathematical model to study the effects of drugs administration on tumor growth dynamics

A mathematical model for describing the cancer growth dynamics in response to anticancer agents administration in xenograft models is discussed. The model consists of a system of ordinary differential equations involving five parameters (three for describing the untreated growth and two for describi...

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Veröffentlicht in:	Mathematical biosciences 2006-04, Vol.200 (2), p.127-151
Hauptverfasser:	Magni, P., Simeoni, M., Poggesi, I., Rocchetti, M., De Nicolao, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer drug discovery Antineoplastic Agents - blood Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - pharmacology Cell Growth Processes - drug effects Cell Line, Tumor Humans Mathematical modelling Mice Mice, Nude Models, Biological Neoplasms, Experimental - drug therapy Neoplasms, Experimental - metabolism Neoplasms, Experimental - pathology Pharmacodynamics models Tumor Burden Tumor growth dynamics Tumor growth model Xenograft Model Antitumor Assays - methods
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