Current status of gene therapy strategies to treat HIV/AIDS

Progress in developing effective gene transfer approaches to treat HIV-1 infection has been steady. Many different transgenes have been reported to inhibit HIV-1 in vitro. However, effective translation of such results to clinical practice, or even to animal models of AIDS, has been challenging. Amo...

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Veröffentlicht in:	Molecular therapy 2005-06, Vol.11 (6), p.823-842
Hauptverfasser:	Strayer, David S, Akkina, Ramesh, Bunnell, Bruce A, Dropulic, Boro, Planelles, Vicente, Pomerantz, Roger J, Rossi, John J, Zaia, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - therapy AIDS Animals Gene therapy Genetic Therapy - methods Genetic Vectors - genetics HIV HIV Infections - therapy HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus Humans Mice Models, Animal Pathology Transgenes Vectors (Biology)
Online-Zugang:	Volltext
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