Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children
PURPOSE:The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants and children. METHODS AND MATERIALS:One hundred eight patients (pts) between 3 months and 5 years of age (77 boys, 31 girls) with clinical suspicion of GER disease were...
Gespeichert in:
| Veröffentlicht in: | Clinical nuclear medicine 2006-05, Vol.31 (5), p.262-265 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 265 |
|---|---|
| container_issue | 5 |
| container_start_page | 262 |
| container_title | Clinical nuclear medicine |
| container_volume | 31 |
| creator | Argon, Murat Duygun, Ulkem Daglioz, Gozde Omür, Ozgur Demir, Esen Aydogdu, Sema |
| description | PURPOSE:The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants and children.
METHODS AND MATERIALS:One hundred eight patients (pts) between 3 months and 5 years of age (77 boys, 31 girls) with clinical suspicion of GER disease were included in the study. Patients were divided into 2 groups according to the age rangegroup A, 0–2 years (57 pts), and group B, 2–5 (51 pts) years. Each group was divided into 2 subgroups according to the scintigraphic study as GER-positive and -negative. Cowʼs milk with Tc-99m sulfur colloid as radiotracer was used. Gastric emptying was expressed as the half emptying time (T1/2). The detection of activity in the esophagus at any time during scintigraphy was considered an indicator of GER episodes. Reflux episodes were graded as grade 1 if activity was detected on one or 2 frames and grade 2 if activity was detected on more than 2 frames.
RESULTS:Forty of the 108 patients (37%) had GER findings on scintigraphy. The comparison of gastric emptying time between positive GER scintigraphy and negative GER scintigraphy groups was not statistically significant in any age group. No association was found between age and rate of gastric emptying time. Although the comparison of T1/2 between grade 1 patients and the GER-negative group was not statistically significant, grade 2 patients showed significant differences and had prolonged gastric emptying times. Mild statistical correlation between the number of reflux episodes and gastric emptying half time was found.
CONCLUSIONS:As a conclusion, the relation between gastroesophageal reflux and delayed gastric emptying cannot be ignored. Our results support delayed gastric emptying to be a pathogenetic factor in gastroesophageal reflux in infants and children. |
| doi_str_mv | 10.1097/01.rlu.0000210500.64440.76 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67876232</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67876232</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4284-f45b905c4f1760ea574299f5c8eab182b7bee6a4547693f685c00d87a36a3cd3</originalsourceid><addsrcrecordid>eNpFkE1r3DAQhkVJaTbb_oViesjN7ujDI7u3ZEmTwEIh5NKTkO1x7FYru5LNJv--3g_IXAaG530HHsa-ccg4lPo78Cy4OYNlBIccIEOlFGQaP7AVzyWmIER5wVYgUaalRnHJrmL8A8CRo_rELjmiEFKKFfv9RM5O_eBj14_JLU17Ip_c2ziFvk7uduP01vuXxPrmdBwoDmNnX8i65IlaN78mvU8efWv9FI_YputdE8h_Zh9b6yJ9Oe81e_5597x5SLe_7h83N9u0VqJQaavyqoS8Vi3XCGRzrURZtnldkK14ISpdEaFVudJYyhaLvAZoCm0lWlk3cs2uT7VjGP7NFCez62NNzllPwxwN6mIRIMUC_jiBdRhiDNSaMfQ7G94MB3PwaoCbxat592qOXo3GJfz1_GWudtS8R88iF0CdgP3gJgrxr5v3FEy3eJq6Y6UELVIBgIdmSA8nJf8DBH6Esw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67876232</pqid></control><display><type>article</type><title>Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children</title><source>Journals@Ovid Ovid Autoload</source><source>MEDLINE</source><creator>Argon, Murat ; Duygun, Ulkem ; Daglioz, Gozde ; Omür, Ozgur ; Demir, Esen ; Aydogdu, Sema</creator><creatorcontrib>Argon, Murat ; Duygun, Ulkem ; Daglioz, Gozde ; Omür, Ozgur ; Demir, Esen ; Aydogdu, Sema</creatorcontrib><description>PURPOSE:The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants and children.
METHODS AND MATERIALS:One hundred eight patients (pts) between 3 months and 5 years of age (77 boys, 31 girls) with clinical suspicion of GER disease were included in the study. Patients were divided into 2 groups according to the age rangegroup A, 0–2 years (57 pts), and group B, 2–5 (51 pts) years. Each group was divided into 2 subgroups according to the scintigraphic study as GER-positive and -negative. Cowʼs milk with Tc-99m sulfur colloid as radiotracer was used. Gastric emptying was expressed as the half emptying time (T1/2). The detection of activity in the esophagus at any time during scintigraphy was considered an indicator of GER episodes. Reflux episodes were graded as grade 1 if activity was detected on one or 2 frames and grade 2 if activity was detected on more than 2 frames.
RESULTS:Forty of the 108 patients (37%) had GER findings on scintigraphy. The comparison of gastric emptying time between positive GER scintigraphy and negative GER scintigraphy groups was not statistically significant in any age group. No association was found between age and rate of gastric emptying time. Although the comparison of T1/2 between grade 1 patients and the GER-negative group was not statistically significant, grade 2 patients showed significant differences and had prolonged gastric emptying times. Mild statistical correlation between the number of reflux episodes and gastric emptying half time was found.
CONCLUSIONS:As a conclusion, the relation between gastroesophageal reflux and delayed gastric emptying cannot be ignored. Our results support delayed gastric emptying to be a pathogenetic factor in gastroesophageal reflux in infants and children.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/01.rlu.0000210500.64440.76</identifier><identifier>PMID: 16622332</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Age Distribution ; Child, Preschool ; Comorbidity ; Female ; Gastric Emptying ; Gastroesophageal Reflux - diagnostic imaging ; Gastroesophageal Reflux - epidemiology ; Humans ; Infant ; Male ; Radionuclide Imaging ; Risk Assessment - methods ; Risk Factors ; Statistics as Topic ; Stomach - diagnostic imaging ; Stomach Diseases - diagnostic imaging ; Stomach Diseases - epidemiology ; Turkey - epidemiology</subject><ispartof>Clinical nuclear medicine, 2006-05, Vol.31 (5), p.262-265</ispartof><rights>2006 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4284-f45b905c4f1760ea574299f5c8eab182b7bee6a4547693f685c00d87a36a3cd3</citedby><cites>FETCH-LOGICAL-c4284-f45b905c4f1760ea574299f5c8eab182b7bee6a4547693f685c00d87a36a3cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16622332$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Argon, Murat</creatorcontrib><creatorcontrib>Duygun, Ulkem</creatorcontrib><creatorcontrib>Daglioz, Gozde</creatorcontrib><creatorcontrib>Omür, Ozgur</creatorcontrib><creatorcontrib>Demir, Esen</creatorcontrib><creatorcontrib>Aydogdu, Sema</creatorcontrib><title>Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children</title><title>Clinical nuclear medicine</title><addtitle>Clin Nucl Med</addtitle><description>PURPOSE:The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants and children.
METHODS AND MATERIALS:One hundred eight patients (pts) between 3 months and 5 years of age (77 boys, 31 girls) with clinical suspicion of GER disease were included in the study. Patients were divided into 2 groups according to the age rangegroup A, 0–2 years (57 pts), and group B, 2–5 (51 pts) years. Each group was divided into 2 subgroups according to the scintigraphic study as GER-positive and -negative. Cowʼs milk with Tc-99m sulfur colloid as radiotracer was used. Gastric emptying was expressed as the half emptying time (T1/2). The detection of activity in the esophagus at any time during scintigraphy was considered an indicator of GER episodes. Reflux episodes were graded as grade 1 if activity was detected on one or 2 frames and grade 2 if activity was detected on more than 2 frames.
RESULTS:Forty of the 108 patients (37%) had GER findings on scintigraphy. The comparison of gastric emptying time between positive GER scintigraphy and negative GER scintigraphy groups was not statistically significant in any age group. No association was found between age and rate of gastric emptying time. Although the comparison of T1/2 between grade 1 patients and the GER-negative group was not statistically significant, grade 2 patients showed significant differences and had prolonged gastric emptying times. Mild statistical correlation between the number of reflux episodes and gastric emptying half time was found.
CONCLUSIONS:As a conclusion, the relation between gastroesophageal reflux and delayed gastric emptying cannot be ignored. Our results support delayed gastric emptying to be a pathogenetic factor in gastroesophageal reflux in infants and children.</description><subject>Age Distribution</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Female</subject><subject>Gastric Emptying</subject><subject>Gastroesophageal Reflux - diagnostic imaging</subject><subject>Gastroesophageal Reflux - epidemiology</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Radionuclide Imaging</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Statistics as Topic</subject><subject>Stomach - diagnostic imaging</subject><subject>Stomach Diseases - diagnostic imaging</subject><subject>Stomach Diseases - epidemiology</subject><subject>Turkey - epidemiology</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1r3DAQhkVJaTbb_oViesjN7ujDI7u3ZEmTwEIh5NKTkO1x7FYru5LNJv--3g_IXAaG530HHsa-ccg4lPo78Cy4OYNlBIccIEOlFGQaP7AVzyWmIER5wVYgUaalRnHJrmL8A8CRo_rELjmiEFKKFfv9RM5O_eBj14_JLU17Ip_c2ziFvk7uduP01vuXxPrmdBwoDmNnX8i65IlaN78mvU8efWv9FI_YputdE8h_Zh9b6yJ9Oe81e_5597x5SLe_7h83N9u0VqJQaavyqoS8Vi3XCGRzrURZtnldkK14ISpdEaFVudJYyhaLvAZoCm0lWlk3cs2uT7VjGP7NFCez62NNzllPwxwN6mIRIMUC_jiBdRhiDNSaMfQ7G94MB3PwaoCbxat592qOXo3GJfz1_GWudtS8R88iF0CdgP3gJgrxr5v3FEy3eJq6Y6UELVIBgIdmSA8nJf8DBH6Esw</recordid><startdate>200605</startdate><enddate>200605</enddate><creator>Argon, Murat</creator><creator>Duygun, Ulkem</creator><creator>Daglioz, Gozde</creator><creator>Omür, Ozgur</creator><creator>Demir, Esen</creator><creator>Aydogdu, Sema</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200605</creationdate><title>Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children</title><author>Argon, Murat ; Duygun, Ulkem ; Daglioz, Gozde ; Omür, Ozgur ; Demir, Esen ; Aydogdu, Sema</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4284-f45b905c4f1760ea574299f5c8eab182b7bee6a4547693f685c00d87a36a3cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Age Distribution</topic><topic>Child, Preschool</topic><topic>Comorbidity</topic><topic>Female</topic><topic>Gastric Emptying</topic><topic>Gastroesophageal Reflux - diagnostic imaging</topic><topic>Gastroesophageal Reflux - epidemiology</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Radionuclide Imaging</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Statistics as Topic</topic><topic>Stomach - diagnostic imaging</topic><topic>Stomach Diseases - diagnostic imaging</topic><topic>Stomach Diseases - epidemiology</topic><topic>Turkey - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Argon, Murat</creatorcontrib><creatorcontrib>Duygun, Ulkem</creatorcontrib><creatorcontrib>Daglioz, Gozde</creatorcontrib><creatorcontrib>Omür, Ozgur</creatorcontrib><creatorcontrib>Demir, Esen</creatorcontrib><creatorcontrib>Aydogdu, Sema</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Argon, Murat</au><au>Duygun, Ulkem</au><au>Daglioz, Gozde</au><au>Omür, Ozgur</au><au>Demir, Esen</au><au>Aydogdu, Sema</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>2006-05</date><risdate>2006</risdate><volume>31</volume><issue>5</issue><spage>262</spage><epage>265</epage><pages>262-265</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><abstract>PURPOSE:The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants and children.
METHODS AND MATERIALS:One hundred eight patients (pts) between 3 months and 5 years of age (77 boys, 31 girls) with clinical suspicion of GER disease were included in the study. Patients were divided into 2 groups according to the age rangegroup A, 0–2 years (57 pts), and group B, 2–5 (51 pts) years. Each group was divided into 2 subgroups according to the scintigraphic study as GER-positive and -negative. Cowʼs milk with Tc-99m sulfur colloid as radiotracer was used. Gastric emptying was expressed as the half emptying time (T1/2). The detection of activity in the esophagus at any time during scintigraphy was considered an indicator of GER episodes. Reflux episodes were graded as grade 1 if activity was detected on one or 2 frames and grade 2 if activity was detected on more than 2 frames.
RESULTS:Forty of the 108 patients (37%) had GER findings on scintigraphy. The comparison of gastric emptying time between positive GER scintigraphy and negative GER scintigraphy groups was not statistically significant in any age group. No association was found between age and rate of gastric emptying time. Although the comparison of T1/2 between grade 1 patients and the GER-negative group was not statistically significant, grade 2 patients showed significant differences and had prolonged gastric emptying times. Mild statistical correlation between the number of reflux episodes and gastric emptying half time was found.
CONCLUSIONS:As a conclusion, the relation between gastroesophageal reflux and delayed gastric emptying cannot be ignored. Our results support delayed gastric emptying to be a pathogenetic factor in gastroesophageal reflux in infants and children.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>16622332</pmid><doi>10.1097/01.rlu.0000210500.64440.76</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-9762 |
| ispartof | Clinical nuclear medicine, 2006-05, Vol.31 (5), p.262-265 |
| issn | 0363-9762 1536-0229 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67876232 |
| source | Journals@Ovid Ovid Autoload; MEDLINE |
| subjects | Age Distribution Child, Preschool Comorbidity Female Gastric Emptying Gastroesophageal Reflux - diagnostic imaging Gastroesophageal Reflux - epidemiology Humans Infant Male Radionuclide Imaging Risk Assessment - methods Risk Factors Statistics as Topic Stomach - diagnostic imaging Stomach Diseases - diagnostic imaging Stomach Diseases - epidemiology Turkey - epidemiology |
| title | Relationship Between Gastric Emptying and Gastroesophageal Reflux in Infants and Children |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T02%3A01%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relationship%20Between%20Gastric%20Emptying%20and%20Gastroesophageal%20Reflux%20in%20Infants%20and%20Children&rft.jtitle=Clinical%20nuclear%20medicine&rft.au=Argon,%20Murat&rft.date=2006-05&rft.volume=31&rft.issue=5&rft.spage=262&rft.epage=265&rft.pages=262-265&rft.issn=0363-9762&rft.eissn=1536-0229&rft_id=info:doi/10.1097/01.rlu.0000210500.64440.76&rft_dat=%3Cproquest_cross%3E67876232%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67876232&rft_id=info:pmid/16622332&rfr_iscdi=true |