Proliferating Hemangioma of Infancy: Successful Treatment with Topical 5% Imiquimod Cream
: A 4‐month‐old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall. The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with t...
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Veröffentlicht in: | Pediatric dermatology 2005-05, Vol.22 (3), p.254-256 |
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container_title | Pediatric dermatology |
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creator | Hazen, Paul G. Carney, James F. Engstrom, Conley W. Turgeon, Karen L. Reep, Michael D. Tanphaichitr, Arrthapol |
description | : A 4‐month‐old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall. The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. The treatment was well tolerated. |
doi_str_mv | 10.1111/j.1525-1470.2005.22318.x |
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The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. 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The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. The treatment was well tolerated.</description><subject>Administration, Topical</subject><subject>Aminoquinolines - therapeutic use</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Female</subject><subject>Hemangioma - drug therapy</subject><subject>Humans</subject><subject>Infant</subject><subject>Medical sciences</subject><subject>Skin Neoplasms - drug therapy</subject><issn>0736-8046</issn><issn>1525-1470</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE9P2zAYhy0Egg72FSZf4JbMjuM_3QEJdUCLECBRNG0Xy3Fs5i5Oip2I9tvPpRVc8cWW_bw_v-8DAMQox2l9X-SYFjTDJUd5gRDNi4Jgka_2wOj9YR-MECcsE6hkR-BLjAuEkGAMH4IjTMeYUS5G4PdD6BpnTVC9a5_h1HjVPrvOK9hZOGutavX6B3wctDYx2qGB82BU703bw1fX_4Xzbum0aiA9hTPvXgbnuxpOEuNPwIFVTTRfd_sxeLq6nE-m2e399WxycZvpkjCR1ZaNCStpXemCMl5oo6murEK0RmPLBS01KSiu0iXCFVJUK21KypUgprS2JsfgbJu7DN3LYGIvvYvaNI1qTTdEybjgyQdPoNiCOnQxBmPlMjivwlpiJDda5UJu7MmNPbnRKt-0ylUq_bb7Y6i8qT8Kdx4TcLoDVEw6bEjeXPzgmKAF4Thx51vu1TVm_ekG5MPPy7djCsi2AS72ZvUeoMK_NCjhVP66u5Z_yCOb3kxv5BX5Dz5XouQ</recordid><startdate>200505</startdate><enddate>200505</enddate><creator>Hazen, Paul G.</creator><creator>Carney, James F.</creator><creator>Engstrom, Conley W.</creator><creator>Turgeon, Karen L.</creator><creator>Reep, Michael D.</creator><creator>Tanphaichitr, Arrthapol</creator><general>Blackwell Science Inc</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200505</creationdate><title>Proliferating Hemangioma of Infancy: Successful Treatment with Topical 5% Imiquimod Cream</title><author>Hazen, Paul G. ; Carney, James F. ; Engstrom, Conley W. ; Turgeon, Karen L. ; Reep, Michael D. ; Tanphaichitr, Arrthapol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4368-df693645dbc25672cec5cbfa05d09f7854c3251b5cb01b0a5cace457a83e4ffd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Administration, Topical</topic><topic>Aminoquinolines - therapeutic use</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Female</topic><topic>Hemangioma - drug therapy</topic><topic>Humans</topic><topic>Infant</topic><topic>Medical sciences</topic><topic>Skin Neoplasms - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hazen, Paul G.</creatorcontrib><creatorcontrib>Carney, James F.</creatorcontrib><creatorcontrib>Engstrom, Conley W.</creatorcontrib><creatorcontrib>Turgeon, Karen L.</creatorcontrib><creatorcontrib>Reep, Michael D.</creatorcontrib><creatorcontrib>Tanphaichitr, Arrthapol</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hazen, Paul G.</au><au>Carney, James F.</au><au>Engstrom, Conley W.</au><au>Turgeon, Karen L.</au><au>Reep, Michael D.</au><au>Tanphaichitr, Arrthapol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proliferating Hemangioma of Infancy: Successful Treatment with Topical 5% Imiquimod Cream</atitle><jtitle>Pediatric dermatology</jtitle><addtitle>Pediatr Dermatol</addtitle><date>2005-05</date><risdate>2005</risdate><volume>22</volume><issue>3</issue><spage>254</spage><epage>256</epage><pages>254-256</pages><issn>0736-8046</issn><eissn>1525-1470</eissn><coden>PEDRDQ</coden><abstract>: A 4‐month‐old girl had a proliferating hemangioma of infancy (infantile hemangioma) affecting the chest wall. The lesion had appeared 1 week after birth, demonstrating both superficial and deep components, and was rapidly enlarging. It had become painful and superficially eroded. Treatment with topical 5% imiquimod cream three times a week was associated with signs of involution after 10 days, and complete resolution after 10 weeks of therapy. The treatment was well tolerated.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Inc</pub><pmid>15916578</pmid><doi>10.1111/j.1525-1470.2005.22318.x</doi><tpages>3</tpages></addata></record> |
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subjects | Administration, Topical Aminoquinolines - therapeutic use Antineoplastic Agents - therapeutic use Biological and medical sciences Dermatology Female Hemangioma - drug therapy Humans Infant Medical sciences Skin Neoplasms - drug therapy |
title | Proliferating Hemangioma of Infancy: Successful Treatment with Topical 5% Imiquimod Cream |
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