The Stem State: Plasticity Is Essential, Whereas Self‐Renewal and Hierarchy Are Optional

The prevailing stem cell concept is derived from the large body of evidence available on the structure of the blood‐generating system. Hemopoiesis is organized such that a multipotent stem cell, endowed with self‐renewal capacity, is viewed as being positioned at the origin of a hierarchical tree of...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2005-06, Vol.23 (6), p.719-726
1. Verfasser:	Zipori, Dov
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Lineage Cell Proliferation Embryo, Mammalian - cytology Hematopoiesis Hematopoietic Stem Cells - cytology Hierarchy Humans Models, Biological Plasticity Regeneration Self‐renewal Stem cells Stem Cells - cytology Stem state
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