Novel indices of ventricular repolarization to screen post myocardial infarction patients
We propose novel indices of ventricular repolarization intervals, the JTp/JT, Tpe/JTp and Tpe/JT ratios. These indices have been compared with the duration of the ventricular repolarization intervals and other ratios in 17 normal subjects and 17 patients with old myocardial infarction. In the interv...
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Veröffentlicht in: | Computers in biology and medicine 2006-05, Vol.36 (5), p.507-515 |
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description | We propose novel indices of ventricular repolarization intervals, the JTp/JT, Tpe/JTp and Tpe/JT ratios. These indices have been compared with the duration of the ventricular repolarization intervals and other ratios in 17 normal subjects and 17 patients with old myocardial infarction. In the intervals and other ratios, the best separation between groups is obtained with the Tpe/QTp and Tpe/QT ratios with 94% sensitivity and 82% specificity, the proposed ratios increased sensitivity to 100% and specificity to 94%. These indices should be further tested to determine their usefulness in discriminating between OMI patients with and without susceptibility to ventricular arrhythmias. |
doi_str_mv | 10.1016/j.compbiomed.2005.03.003 |
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These indices should be further tested to determine their usefulness in discriminating between OMI patients with and without susceptibility to ventricular arrhythmias.</description><identifier>ISSN: 0010-4825</identifier><identifier>EISSN: 1879-0534</identifier><identifier>DOI: 10.1016/j.compbiomed.2005.03.003</identifier><identifier>PMID: 15899477</identifier><identifier>CODEN: CBMDAW</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Adult ; Algorithms ; Electrocardiography ; Female ; Heart Conduction System ; Heart Ventricles - pathology ; Humans ; Intervals ratios ; JT interval ; JTp interval ; Male ; Middle Aged ; Models, Cardiovascular ; Myocardial infarction ; Myocardial Infarction - diagnosis ; Myocardial Infarction - pathology ; Myocardial Infarction - therapy ; QT interval ; Risk Factors ; Sensitivity and Specificity ; Signal Processing, Computer-Assisted ; Tpe interval ; Ventricular repolarization</subject><ispartof>Computers in biology and medicine, 2006-05, Vol.36 (5), p.507-515</ispartof><rights>2005 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-587e50d16aa5ed2c568c4d86b27eb4ad40688b94b6dd3c373d1804cb0c3352d43</citedby><cites>FETCH-LOGICAL-c481t-587e50d16aa5ed2c568c4d86b27eb4ad40688b94b6dd3c373d1804cb0c3352d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1030086975?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15899477$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alvarado-Serrano, Carlos</creatorcontrib><creatorcontrib>Ramos-Castro, Juan</creatorcontrib><creatorcontrib>Pallàs-Areny, Ramon</creatorcontrib><title>Novel indices of ventricular repolarization to screen post myocardial infarction patients</title><title>Computers in biology and medicine</title><addtitle>Comput Biol Med</addtitle><description>We propose novel indices of ventricular repolarization intervals, the JTp/JT, Tpe/JTp and Tpe/JT ratios. These indices have been compared with the duration of the ventricular repolarization intervals and other ratios in 17 normal subjects and 17 patients with old myocardial infarction. In the intervals and other ratios, the best separation between groups is obtained with the Tpe/QTp and Tpe/QT ratios with 94% sensitivity and 82% specificity, the proposed ratios increased sensitivity to 100% and specificity to 94%. These indices should be further tested to determine their usefulness in discriminating between OMI patients with and without susceptibility to ventricular arrhythmias.</description><subject>Adult</subject><subject>Algorithms</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart Conduction System</subject><subject>Heart Ventricles - pathology</subject><subject>Humans</subject><subject>Intervals ratios</subject><subject>JT interval</subject><subject>JTp interval</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Models, Cardiovascular</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - pathology</subject><subject>Myocardial Infarction - therapy</subject><subject>QT interval</subject><subject>Risk Factors</subject><subject>Sensitivity and Specificity</subject><subject>Signal Processing, Computer-Assisted</subject><subject>Tpe interval</subject><subject>Ventricular repolarization</subject><issn>0010-4825</issn><issn>1879-0534</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkcFq3DAQhkVJaTZJX6EIArnZHVmSJR_T0DaF0F7aQ09ClmZBi205kr2QPn212aWBXnKag77_HzQfIZRBzYC1H3e1i-PchziirxsAWQOvAfgbsmFadRVILs7IBoBBJXQjz8lFzjsAEMDhHTlnUnedUGpDfn-PexxomHxwmGnc0j1OSwpuHWyiCedYZvhjlxAnukSaXUKc6BzzQsen6GzywR7yW5vcMzQXtlTkK_J2a4eM70_zkvz68vnn3X318OPrt7vbh8oJzZZKaoUSPGutlegbJ1vthNdt3yjshfUCWq37TvSt99xxxT3TIFwPjnPZeMEvyc2xd07xccW8mDFkh8NgJ4xrNq3SCjiDV0HWCcFY0xTw-j9wF9c0lU-YUgOg207JQukj5VLMOeHWzCmMNj0VyBwsmZ15sWQOlgxwUyyV6IfTgrU_vP0LnrQU4NMRwHK4fcBksitHdehDQrcYH8PrW_4CSSCpKg</recordid><startdate>20060501</startdate><enddate>20060501</enddate><creator>Alvarado-Serrano, Carlos</creator><creator>Ramos-Castro, Juan</creator><creator>Pallàs-Areny, Ramon</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AL</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0N</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7QO</scope><scope>7X8</scope></search><sort><creationdate>20060501</creationdate><title>Novel indices of ventricular repolarization to screen post myocardial infarction patients</title><author>Alvarado-Serrano, Carlos ; Ramos-Castro, Juan ; Pallàs-Areny, Ramon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-587e50d16aa5ed2c568c4d86b27eb4ad40688b94b6dd3c373d1804cb0c3352d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Algorithms</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Heart Conduction System</topic><topic>Heart Ventricles - pathology</topic><topic>Humans</topic><topic>Intervals ratios</topic><topic>JT interval</topic><topic>JTp interval</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Models, Cardiovascular</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - pathology</topic><topic>Myocardial Infarction - therapy</topic><topic>QT interval</topic><topic>Risk Factors</topic><topic>Sensitivity and Specificity</topic><topic>Signal Processing, Computer-Assisted</topic><topic>Tpe interval</topic><topic>Ventricular repolarization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alvarado-Serrano, Carlos</creatorcontrib><creatorcontrib>Ramos-Castro, Juan</creatorcontrib><creatorcontrib>Pallàs-Areny, Ramon</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Computing Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Computer Science Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Computing Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Biotechnology Research Abstracts</collection><collection>MEDLINE - 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These indices have been compared with the duration of the ventricular repolarization intervals and other ratios in 17 normal subjects and 17 patients with old myocardial infarction. In the intervals and other ratios, the best separation between groups is obtained with the Tpe/QTp and Tpe/QT ratios with 94% sensitivity and 82% specificity, the proposed ratios increased sensitivity to 100% and specificity to 94%. These indices should be further tested to determine their usefulness in discriminating between OMI patients with and without susceptibility to ventricular arrhythmias.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>15899477</pmid><doi>10.1016/j.compbiomed.2005.03.003</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Algorithms Electrocardiography Female Heart Conduction System Heart Ventricles - pathology Humans Intervals ratios JT interval JTp interval Male Middle Aged Models, Cardiovascular Myocardial infarction Myocardial Infarction - diagnosis Myocardial Infarction - pathology Myocardial Infarction - therapy QT interval Risk Factors Sensitivity and Specificity Signal Processing, Computer-Assisted Tpe interval Ventricular repolarization |
title | Novel indices of ventricular repolarization to screen post myocardial infarction patients |
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