Activation of the Mitochondrial Apoptotic Pathway in a Rat Model of Central Retinal Artery Occlusion

Apoptosis is known to play a role in cell death in transient retinal ischemia. Little is known about the specific molecular pathways involved. The purpose of the current study was to evaluate a rat model of central retinal artery occlusion (CRAO) that simulates the clinical features of CRAO in human...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Investigative ophthalmology & visual science 2005-06, Vol.46 (6), p.2133-2139
Hauptverfasser:	Zhang, Yi, Cho, Chang-Ho, Atchaneeyasakul, La-ongsri, McFarland, Trevor, Appukuttan, Binoy, Stout, J. Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Amacrine Cells - pathology Animals Apoptosis bcl-2-Associated X Protein Biological and medical sciences Blotting, Western Caspase 9 Caspases - metabolism Cytochromes c - metabolism Cytosol - metabolism Disease Models, Animal Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology In Situ Nick-End Labeling Male Mitochondria - metabolism Protein Transport Proto-Oncogene Proteins c-bcl-2 - metabolism Rats Rats, Sprague-Dawley Retinal Artery Occlusion - metabolism Retinal Artery Occlusion - pathology Retinal Ganglion Cells - pathology Time Factors Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!