A missense mutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy

Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns and mediate the activation of NF-κB and the production of proinflammatory cytokines, which is critical for the innate immune system. TLR3 recognizes both double-stranded RNA and the influenza A virus. Since influenza-associa...

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Veröffentlicht in:Clinical Immunology 2006-05, Vol.119 (2), p.188-194
Hauptverfasser: Hidaka, Fumio, Matsuo, Susumu, Muta, Tatsushi, Takeshige, Koichiro, Mizukami, Tomoyuki, Nunoi, Hiroyuki
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Sprache:eng
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